Thermo Fisher Scientific Maybridge Chiral Resolution Screening and Purification Kits

Thermo Fisher Scientific has introduced Maybridge Chiral Resolution Screening and Purification Kits to give organic chemists simple and rapid access to optically pure chiral compounds from their racemic mixtures.

Identifying the best separation conditions under which a target compound can be isolated with optimal yield and purity, can take days, or even weeks. The portfolio of ready-to-use kits reduces development time to just one day, with as little as 0.4 mmol of racemate required.

As a commonly used process to obtain optically pure chiral compounds from their racemic mixtures, diastereomeric crystallisation requires careful optimisation of process conditions. The kits consist of 384 different combinations of resolving agents and solvents, for both acid- and amine-based resolutions, to increase the chances of finding the optimal separation conditions. With resolving agents and solvents pre-dispensed in 96-well plates, the kits provide easily identifiable results when screening and simple recovery and purification of enantiomers.

An online brochure provides an overview of key features and benefits, how to use the kits and a selection guide. The brochure can be downloaded from www.maybridge.com/Images/pdfs/MB_Chiral_broch_01_2012_v14.pdf.