Thermo Scientific FAIMS Pro interface

Proteomic scientists can now take advantage of a differential ion mobility device that seamlessly integrates with high-resolution mass spectrometers to provide workflow efficiency and data quality for experiments ranging from the discovery of disease biomarkers to the identification of new therapeutic targets. When integrated with a high-resolution mass spectrometer, the Thermo Scientific FAIMS Pro interface is designed to increase the breadth and depth of proteins scientists can identify while reducing time-consuming sample preparation steps.

The interface provides analytical performance that is expected to reduce sample and spectral complexity, improve selectivity and increase coverage of the proteome. It is said to enable considerably more sample depth per unit time and could eliminate the need for pre-fractionation of peptides for most applications.

The product provides fast, high-quality results, enhancing instrument selectivity and detection limits through gas phase fractionation and reduced matrix interference. It leverages menu-driven software to design methods using preconfigured parameters, increasing productivity and simplifying use.

The device is said to reduce sample fractionation steps, which can help save time and maintenance through increased productivity. It achieves high data quality on sample-limited studies through an interface designed to improve nano, capillary and microflow applications.

When the interface is combined with the Thermo Scientific Orbitrap Fusion Lumos Tribrid or Thermo Scientific Orbitrap Fusion Tribrid high-resolution mass spectrometers, laboratories have a comprehensive solution to improve selectivity and ensure increased productivity across a range of proteomics workflows.