Unchained Labs Stunner instrument for protein analysis

Friday, 25 January, 2019 | Supplied by: AXT Pty Ltd



The Stunner from Unchained Labs can measure both protein size and concentration in a single instrument. It is designed specifically for protein and biologics researchers.

Using UV/Vis spectroscopy and DLS (dynamic light scattering), the product is able to simultaneously measure protein concentration, hydrodynamic size and polydispersity, and to detect aggregates. This saves the user time, helping them to narrow down optimal formulations more quickly.

The product requires only a 2 µL sample, with no need for dilution or sample preparation. The system can process single samples in as little as 1 min. For higher throughputs, the concentration of an entire 96 well-plate can be completed in 12 min, or both concentration and sizing in 1 h. To provide the user with a more comprehensive picture of how their formulation behaves, it can also determine the effects of parameters such as storage, agitation and changes to process chemistry.

The instrument measures the concentration of each sample in a series using real-time DLS, ensuring correct results and letting the user know if their sample is prone to aggregation. The user can also determine the stability of their protein formulation using a host of stand methods or they can create their own custom aggregation index.

Online: www.axt.com.au
Phone: 02 9450 1359
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