9/11's first responders face risk of developing COPD
Twenty years on from the September 11 attacks, rescue and recovery workers and volunteers who attended the World Trade Center site are beginning to develop chronic obstructive pulmonary disease (COPD) often following a previous diagnosis of asthma, according to research presented at the European Respiratory Society (ERS) International Congress.
COPD is a chronic lung condition that causes breathing difficulties, coughing and wheezing that get worse over time. It mainly affects older people who smoke, but occupational and environmental exposures are increasingly recognised as risk factors.
The new study included 17,996 people who had worked at the World Trade Center site. Each of these workers took part in spirometry tests to measure their lung health on at least two occasions between 2002 and 2018. These tests assess how much air a person can breathe out in one forced breath, and they are used to help diagnose COPD and asthma. The researchers compared those data with information on when each person arrived to work at the World Trade Center site, as well as other factors that can influence lung health.
The results showed that workers who arrived in the first day or two, when the smoke and dust were at their worst, were more likely to have poorer lung function. The study showed that 586 (3.3%) of the workers had developed spirometrically defined COPD so far, with those who arrived early to the site at the greatest risk (around 30% higher than those who arrived to work later on), even after adjusting for tobacco smoking and obesity. Around a quarter of the people diagnosed with COPD were lifetime non-smokers. The study also showed that COPD often followed an earlier diagnosis of asthma and that about 40% of those workers with COPD had features of both diseases, known as asthma-COPD overlap or ACO.
“Many of these workers were non-smokers and in their early 40s in 2001, and COPD is rare in that age group,” said Professor Rafael E de la Hoz from the Icahn School of Medicine at Mount Sinai, who presented the study. “Twenty years on from their work at the World Trade Center site, and despite decreasing rates of smoking, we are starting to see cases of COPD emerge. Our study shows that those facing the greatest risk are those who worked on the site in the first day or two after the towers collapsed and in those who had previously been diagnosed with asthma.”
The researchers say this is one of the largest and most detailed prospective studies on a group of workers exposed to such high levels of smoke and dust. Its findings could help people who have been exposed at the World Trade Center site, or following other disasters, by ensuring that long-term health problems such as COPD are diagnosed and treated as soon as possible.
“It’s important that we continue to monitor these workers to understand the long-term impacts of their exposure while working on the site, because some conditions can take many years to develop,” Prof de la Hoz said.
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