Lonza PyroTec PRO with PyroWave Reader for endotoxin testing

Lonza has announced an expansion to its PyroTec PRO automated robotic system for endotoxin testing. The PyroWave Reader add-on has been designed specifically for use with the sustainable PyroGene Recombinant Factor C (rFC) Assay. This brings a third test type option to the platform, allowing QC microbiologists to choose the endotoxin test method best suited to their testing needs. The PyroTec PRO, now compatible with Lonza’s PYROGENT-5000 Turbidimetric LAL (Limulus Amebocyte Lysate) Assay, Kinetic-QCL Chromogenic LAL Assay and PyroGene rFC Assay, therefore expands the options available for streamlined, automated endotoxin testing.

The PyroGene rFC Assay is an animal-free method for endotoxin detection that works through a single enzymatic step. It has been shown to be equivalent to other photometric endotoxin methods that use LAL to detect endotoxins according to the parameters listed in the USP chapter <1225> ‘Validation of Compendial Procedures’. These parameters include linearity, specificity, precision, accuracy and limit of detection.

The need for dependable endotoxin testing technology continues to grow, especially with the pharmaceutical industry increasingly focusing on the development of innovative biotherapeutics that carry a higher risk of endotoxin contamination. Through process optimisation and automation of routine manual tasks, the PyroTec PRO is designed to help users streamline and improve the performance of the QC laboratory, increasing lab efficiency and productivity. Automated endotoxin testing can also reduce the potential for human error. Able to easily accommodate different assay types in the same run, and powered by the WinKQCL Endotoxin Analysis Software, the complete system should further increase the efficiencies and data integrity gained from automated endotoxin testing.