Model for testing anti-cancer drugs
Monday, 16 July, 2001
Working with Dr Kay in the Department of Pathology, University of Western Australia, Janelle Pelham has begun to model the testing of specific anti-cancer drugs on the domestic dog.
The work of understanding the role of DNA methylation in cancer has led the Department to establish that the attachment of methyl groups to DNA is defective in many different types of cancers. As no appropriate model exists for testing new therapeutic agents designed to correct these DNA methylation defects, the domestic dog was chosen.
The reason for this is that many forms of human cancer also develop spontaneously in dogs, that as in humans genomic DNA is profoundly hypomethylated in dogs suffering from lymphoma and leukemia, and that the domestic dog's environment is similar to a human's.
AXT to distribute NT-MDT atomic force microscopes
Scientific equipment supplier AXT has announced a partnership with atomic force microscope (AFM)...
Epigenetic patterns differentiate triple-negative breast cancers
Australian researchers have identified a new method that could help tell the difference between...
Combined effect of pollutants studied in the Arctic
Researchers from the Fram Centre in Norway are conducting studies in Arctic waters to determine...
