Immortalised human neural progenitor cell lines

Millipore has released the ReNcell product line of human immortalised neural somatic stem cell lines.

The ReNcell products are a convenient solution for users needing reproducible results with neurons easily derived from human cells. These progenitor cells are particularly useful in drug discovery applications, where the development of these pathways can be monitored during screening.

The ReNcell product line consists of two cell lines of immortalised human neural progenitor cells and media for the maintenance, expansion and freezing of the cells. These cell lines and media are available either individually or as a kit. This product line is a result of a distribution agreement announced earlier this year between Millipore Corporation and ReNeuron Group plc.

These immortalised human neural progenitor cells have the ability to readily differentiate into neural cell types and will replicate indefinitely. ReNcell immortalised cells display the same marker patterns as normal cells and are able to grow and remain stable after culturing.

Neurons derived from these cells show physiological properties of mature neurons, which is valuable when validating results. Even after prolonged passages, ReNcell cells maintain karyotype stability and will not differentiate without an external stimulus.