Pipette tips for proteomics

Sunday, 23 November, 2003 | Supplied by: Varian Australia Pty Ltd


Varian's OMIX pipette tips for microextractions feature a monolithic sorbent technology, achieving up to a 3-fold improvement in RSDs (relative standard deviations) and isolating up to 38% more peptide for more accurate and reproducible mass analysis.

Scientists focusing on proteomics research must remove salts, or desalt, and concentrate samples before analysis with Maldi-TOF mass spectrometry or LC/MS/MS. Proteomics researchers work with limited sample volumes so micro-volume purification devices are critical to improving sensitivity and achieving more reliable and consistent identification and characterisation of proteins.

Varian's OMIX tips contain a small bed of functionalised monolithic sorbent inserted inside a pipette tip. This miniaturised SPE (solid phase extraction) bed accommodates micro-litre loading and elution volumes required by proteomic scientists with volume limited samples.

An advantage of OMIX tips over other µC18 tips is a strongly improved flow behaviour, which is very important for viscous samples. Inline process assurance techniques, including confirming the chemistry of the sorbent, provide more dependable tip-to-tip performance, alleviating lost samples, and present a cost-effective option. Additionally the proprietary monolithic sorbent technology ensures enhanced flow characteristics, providing faster and more uniform flow, and improved binding capacities for higher recoveries.

Online: www.varianinc.com
Phone: 03 95607133
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