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Sigma-Aldrich Pty Ltd

At Science 2000, Sigma-Aldrich will present their latest Sigma, Supelco, Fluka/Riedel-de Haen and Flavours & Fragrances catalogues, as well as give you the chance to reserve your copies of the "soon-to-be-released", new Aldrich catalogue and new Life Science catalogue. Find out about all the latest Sigma-Aldrich focuses as well as the new lab essesntials program, for all your everyday laboratory needs. Visit their stand to requrest your free copy of periodic table and Risk & Safety posters from Riedel-de Haen or for more product information visit our web page at www.sigma-aldrich.com.


Website: http://www.sigma-aldrich.com
Email: ausmail@sial.com
Phone: 1800 800 097
Fax: 1800 800 096
Address:
2/14 Anella Avenue , Castle Hill NSW 2154 (Directions)

Products

DyNAbind DNA-encoded library (DEL) kits

DyNAbind's fragment-based DNA-encoded library (DEL) kit, containing more than 370,000 paired arrangements of molecular fragments, is designed to provide improved signal-to-noise ratios and reduced false positive hit rates.

Cerilliant Snap-N-Spike stable-labelled internal standards of antifungal agents

Cerilliant has introduced five stable-labelled internal standards of the antifungal agents fluconazole, itraconazole, ketoconazole, posaconazole and voriconazole at 1 mg/mL concentrations.

Sigma-Aldrich XCell Science genetically engineered iPSC-derived neural disease cells

Sigma-Aldrich has entered into an agreement with XCell Science to launch genetically engineered human neural differentiated cells and accompanying culture media developed to advance the research of neurological diseases. The products provide versatile tools for the study of central nervous system (CNS) disorders, as well as for drug screening and toxicology applications in the neural space.

SAFC EX-CELL Advanced CHO Fed-batch System

SAFC Commercial has launched the EX-CELL Advanced product line. Designed to address the needs of an industry where speed to market is important, the product line provides for increased performance, streamlines regulatory compliance and offers the supply chain security needed in the current biopharmaceutical environment.

Supelco Ascentis Express 2.0 micron UHPLC column line

Supelco has launched the Ascentis Express 2.0 micron, a high-speed, ultrahigh-performance liquid chromatography (UHPLC) column platform based on the Fused-Core particle design. Ascentis Express 2.0 micron Fused-Core particles are designed to provide UHPLC performance while addressing the disadvantages in existing sub-2 micron UHPLC columns.

Sigma Life Science OligoEvaluator v2.0 oligonucleotide sequence calculator

Sigma Life Science offers an enhanced version of its online oligonucleotide sequence calculator. OligoEvaluator has the functionality to help users make critical experimental decisions - 10 sequences at a time.

Sigma Life Science gene synthesis service

Gene synthesis is an efficient alternative to molecular cloning for custom gene production, eliminating the struggle of cloning and building genes to the user's specifications.

Cerilliant Snap-N-Spike reference standards of designer psychedelics

Cerilliant has introduced six certified Snap-N-Spike reference standards of designer psychedelics in the NBOMe (N-methoxybenzyl-substituted) class of phenethylamines.

Sigma-Aldrich KiCqStart primer pairs

Sigma-Aldrich's ready-to-order, predesigned primer pairs make quantifying gene expression simple. The product is available as up to three sets of forward and reverse primer pairs for all available genes from common model organisms.

Sigma-Aldrich TruPAGE precast gels

TruPAGE precast gels are designed to provide precise SDS-PAGE protein separation consistently with every consecutive experiment. The gels are formulated with TEA-Tricine and provide a running environment that helps prevent protein modification during the course of the experiment.

Cerilliant Certified Spiking Solutions of corticosteroids

Cerilliant has introduced four Certified Spiking Solutions of the corticosteroids pregnenolone, 17alpha-hydroxypregnenolone, cortisone and 11-deoxycorticosterone at concentrations of 100 µg/mL in methanol.

Sigma-Aldrich ISO 13485 oligonucleotides

Sigma-Aldrich offers custom DNA primers and qPCR probes for molecular diagnostics. Services include scale-up capabilities, process development, and analytical methods development.

Sigma Life Science Onyx Quencher for qPCR

A quencher for quantitative real-time PCR (qPCR) that improves assay signal quality, Onyx Quencher adds to Sigma Life Science's portfolio of qPCR probes, reagents and oligonucleotide services.

Sigma-Aldrich OligoArchitect Online v4.0

Sigma Life Science offers an enhanced version of its comprehensive online qPCR assay design tool - OligoArchitect. It is a freely available online tool for the automated design of primers and probes for quantitative real-time PCR assays.

Sigma-Aldrich custom oligonucleotides

Sigma-Aldrich supplies custom DNA and RNA oligonucleotides to the global life science research community.

Sigma Life Science Mission Synthetic and Lentiviral microRNA Inhibitors

Sigma Life Science, through a collaboration with Drs Hideo Iba and Takeshi Haraguchi at the University of Tokyo, has released Mission Synthetic and Lentiviral microRNA Inhibitors based on the tough decoy (TuD) design for the long-term suppression of any miRNA endogenous to humans or mice.

Sigma-Aldrich OligoArchitect v3.0

Sigma Life Science’s comprehensive online qPCR design tool, OligoArchitect, can be used for all primer and probe design requirements.

Wilmad NMR Precision Tubes

NMR Precision Tubes are manufactured from borosilicate glass that meets the requirement of Type 1 Class A glass from ASTM E438.

Sigma-Aldrich Mix-n-Stain CF dye antibody labelling kits

Mix-n-Stain antibody labelling kits dramatically simplify the process of antibody labelling. The kits enable a researcher to covalently label 1-100 μg of an antibody with one of the company’s bright and photostable CF dyes or biotin in 30 min and ~100% yield.

SAFC integrated chiral chemistry offer

Sigma-Aldrich has announced that its custom manufacturing and services business unit, SAFC, will consolidate its chiral chromatography screening and small-scale purification operations and locate them at its Pharmorphix Solid State Research Laboratories in Cambridge, UK, to support its new integrated chiral chemistry offer.

SAFC CHOZN Platform system

Sigma-Aldrich has announced that its custom manufacturing and services business unit, SAFC, is launching the CHOZN Platform system, a CHO (Chinese hamster ovary) cell expression system that allows for faster, simpler selection and scale-up of high-producing clones for the production of recombinant protein drugs.

Sigma Aldrich SLB-IL111 for FAME column

The extremely polar ionic liquid SLB-IL111 column is claimed to have the most orthogonal selectivity compared to commonly-used, non-polar and intermediate polar columns, providing increased selectivity for polar and polarisable analytes.

Ascentis Express HPLC columns

Ascentis Express HPLC columns, through the use of fused-core particle technology, provide both the high speed and high efficiencies of sub-2 μm particles while maintaining lower backpressures. This combination benefits UPLC (or other ultra high pressure system) users as well as conventional HPLC users, with the increased efficiency of the columns equating to the use of shorter columns and lower volume of solvents.

Sigma Life Science CompoZr Knockout ZFN extended range

Sigma Life Science has announced a further development of its CompoZr zinc finger nuclease (ZFN) technology with the release of its Knockout ZFNs covering the entire genomes of both mice and rats. The expansion of the Knockout ZFNs for every mouse and rat gene is in its initial phase, which complements the existing range of Knockout ZFNs for the entire human genome.

Sigma Life Science CompoZr Oncology Disease Model portfolio

Sigma Life Science has expanded its CompoZr Oncology Disease Model portfolio with the release of the first in its collection of breast cancer-specific knockout and knockin cell lines for drug discovery and research.

SAFC CHOZN Zinc Finger Nuclease-modified Chinese Hamster Ovary cell lines

SAFC has released its first offering in a product line of Zinc Finger Nuclease (ZFN)-modified Chinese Hamster Ovary (CHO) cell lines.

Corning HyperStack cell culture vessel

The HyperStack Cell Culture Vessel is the latest addition to Corning’s High Yield PERformance (HYPER) Platform. This product line combines the best of two Corning products; the CellStack Culture Chamber and HyperFlask vessel. The use of gas-permeable film technology in the CellStack Culture Chamber allows the HyperStack vessel to be an efficient, scalable cell culture vessel for adherent cell culture.

Corning DeckWorks pipette tips

Corning DeckWorks pipette tips are made in a controlled moulding environment to ensure accuracy and precision across all tip volumes. Medical-grade resins and production excellence allow for full certification as nonpyrogenic, human DNA free, RNase/DNase free and sterility assurance level 10-3.

Sigma Aldrich Ascentis Express HPLC columns

Ascentis Express HPLC columns, through the use of Fused-Core particle technology, provide both high speed and high efficiencies of sub-2 µm particles while maintaining lower backpressures. The combination of high efficiency and low backpressure benefits UPLC (or other ultrahigh-pressure system) users as well as conventional HPLC users.

Sigma Life Science and Cofactor Genomics rat genome database

Sigma Life Science’s SAGE Labs initiative has partnered with Cofactor Genomics in an effort to sequence genomes for six of the most widely used strains of rat. As part of the agreement, Cofactor Genomics plans to generate and analyse sequence data using next-generation sequencing systems, while SAGE Labs plans to provide the samples and to host a new, free public database at sageresearchmodels.com in late 2011. The database will include exclusive genomic information and analysis tools.

Corning’s Synthemax and Osteo Assay surfaces

Corning Synthemax surface, a novel synthetic surface that supports the growth and differentiation of stem cells, is now available as a 6-well plate or 75 cm flask.

Sigma Life Science engineered mammalian cell lines

Sigma Life Science has released a range of engineered mammalian cell lines. The product range combines Sigma’s CompoZr zinc finger nuclease (ZFN) technology with the company’s experience in gene silencing to offer tools for drug discovery, compound screening and fundamental research applications.

SAFC ProClin B-119 biocide

SAFC has launched a ‘ready-to-use’ solution-based biocide, ProClin B-119.

Supelco Ascentis Express Peptide ES-C18 columns

Supelco Ascentis Express Peptide ES-C18 columns are a high-speed, high-performance liquid chromatography (HPLC) column based on a 160 Å Fused-Core particle design. This column design exhibits very high column efficiency, providing a stable, reversed-phase packing with a pore structure and pore size that is optimised for reversed-phase HPLC separations of peptides and polypeptides.

Sigma Life Science knockout rat models for ADME/Tox applications

Sigma Life Science has extended its portfolio of knockout rat models with a suite of models designed to facilitate more predictive absorption, distribution, metabolism, excretion and toxicity (ADME/Tox) studies.

Supelco Supel-Select HLB SPE

Supelco Supel-Select HLB SPE is hydrophilic modified styrene-based polymer developed for the solid-phase extraction of a highly broad range of compounds from aqueous samples.

Corning and Sigma Aldrich cell culture consumables

Sigma Aldrich and Corning Life Sciences have forged a closer global alliance to bring better service and value to their users.

Authenticated cell lines

In collaboration with the European Collection of Cell Cultures (ECACC) and its partners, Sigma-Aldrich now offers access to approximately 700 authenticated cell lines from ECACC’s general collection. The most commonly used lines are now stored in Australia and available within days, rather than weeks, of ordering.

HPLC columns for reduced acetonitrile use

The increased efficiency of the Fused-Core particle in the Ascentis Express HPLC columns enables users to use shorter columns and save acetonitrile by more than 70%.

Raw materials for molecular diagnostics manufacturing

SAFC Supply Solutions, a business segment of SAFC, a member of the Sigma-Aldrich Group, has launched a diverse product offering to meet the demands of the molecular diagnostics market and provide single-point access to a broad range of regulatory-compliant and custom-manufactured raw materials.

Catalogues

Sigma-Aldrich has available its flagship analytical catalogues from Fluka and Supelco.

Ascentis Express HPLC columns

The increased efficiency of the Fused-Core particle in the Ascentis Express HPLC columns enables users to use shorter columns and reduce acetonitrile use by up to 70%.

Serological pipette

Excel Scientific’s redesigned 50 mL serological pipettes are constructed from high-clarity virgin polystyrene.

Protein standards

The Proteomics Dynamic Range Standard, UPS2, is an enhancement of Sigma Aldrich’s original Universal Proteomics Standard (UPS1). The same mixture of 48 human proteins has been formulated into a range of concentrations, ranging from 0.5 fmoles to 50 pmoles.

Plasmid purification kit

The GenElute HP 96-well plasmid miniprep kit for DNA purification is suitable for a variety of pharmaceutical and biotechnology research applications, providing rapid purification of plasmid DNA that can generate transfection-grade plasmid with high viral titers.

Antibody-based protein depletion column

The Seppro IgY depletion platform is an antibody-based technology for processing plasma, serum and plant samples. It enables researchers to detect and analyse commonly obscured biomarkers in samples by removing highly abundant proteins.

GC septa

Supelco moulded Thermogreen LB-2 GC septa are available in two versions, without and with an injection hole.

Materials science catalogue

Aldrich has released its Materials Science catalogue. The free catalogue features more than 4000 products for research in alternative energy, organic electronics, metal and ceramic science, nanomaterials, micro/nanoelectronics and polymer science. Each chapter contains technical information and highlights from some of the recent advances in these fields.

Single-wall carbon nanotubes

SWeNT’s single-wall carbon nanotubes consist of a hollow cylinder of carbon with a diameter of approximately 1 nm.

Whole transcriptome amplification

Sigma-Aldrich has launched the TransPlex Whole Transcriptome Amplification (WTA2) technology. TransPlex technology is said to be a fast, sensitive and robust method for amplifying total RNA from a variety of sample tissue sources such as animals, plants and microorganisms.

Luminescence films

Excel Scientific has introduced BrightMax adhesive white vinyl films. Used with white clear-bottom microplates, the films help to maximise signals in luminescence assays.

Kit for epigenetic research

The Imprint Chromatin Immunoprecipitation (ChIP) kit for epigenetic research provides a complete solution for chromatin immunoprecipitation, including columns and reagents for DNA purification as well as an integrated protocol for ChIP DNA amplification with the GenomePlex whole genome amplification kit.

Antibodies

Prestige Antibodies, powered by Atlas Antibodies, are developed and validated by the Human Proteome Resource (HPR) project.

Gene-based search tool

Your Favorite Gene (www.sigma.com/yfg) is a comprehensive, web-based search tool that matches genes of interest against thousands of Sigma-Aldrich research products. This flexible search engine matches 150,000 shRNAs, 725,000 siRNAs, 4000 antibodies, proteins and kits, and 1000 bioactive small molecules to specific genes of interest.

Internet nutrition tool

Sigma-Aldrich has enhanced its Bioactive Nutrient Explorer. This internet-based tool has been specifically designed to help nutrition and animal scientists, medical researchers, biologists and analytical chemists studying dietary plants and supplements locate the chemicals and kits they need to support their work.

Antibody array

The Panorama Antibody Microarray XPRESS Profiler725 is a high-throughput tool for multiplex protein expression profiling of serum, cell or tissue extracts.

Functional protein array

The Panorama Human Signal Transduction Protein Array, developed in conjunction with Procognia Ltd, contains 259 full-length proteins that are involved in key cellular processes including proliferation, differentiation and apoptosis.

Gene knockout vectors

Sigma-Aldrich has introduced TargeTron vectors designed for use with the TargeTron gene knockout system. The vectors enhance the capabilities and increase the flexibility of the system providing researchers with a targeted method to knock out multiple genes in prokaryotic organisms, to generate knockouts without using selection or by using removable selection and to produce knockouts in organisms lacking a source of T7 RNA polymerase.

Gene knockout vectors

Sigma-Aldrich has introduced TargeTron vectors designed for use with the TargeTron gene knockout system. The vectors enhance the capabilities and increase the flexibility of the system providing researchers with a targeted method to knock out multiple genes in prokaryotic organisms, to generate knockouts without using selection or by using removable selection and to produce knockouts in organisms lacking a source of T7 RNA polymerase.

Stain and dye information

The Stain Expert is a web-based application specifically developed to assist users with the retrieval of stain and dye information.

RNAi libraries

Sigma-Aldrich has introduced the Mission RNAi product line, including the first available formats for the RNAi Consortium (TRC) shRNA libraries.

Fast DNA extraction

Sigma-Aldrich has introduced a tissue PCR kit that contains reagents to rapidly extract genomic DNA from tissue or cells and amplify targets of interest by PCR. Extract-N-Amp Tissue PCR kit (Product number XNAT) offers a single-step extraction of tissue genomic DNA in less than 15 minutes.

Quantitative PCR

SYBR Green JumpStart Taq ReadyMix is available in both standard and capillary formulations. It combines the advantage of a hot start enzyme with a ready-to-use mix of SYBR Green 1, dNTPs and optimised buffer solutions.

Quantitative PCR

SYBR Green JumpStart Taq ReadyMix is available in both standard and capillary formulations. It combines the advantage of a hot start enzyme with a ready-to-use mix of SYBR Green 1, dNTPs and optimised buffer solutions.

Maldi-mass spectrometry matrices

Maldi (matrix-assisted laser desorption/ionisation), a laser-based soft ionisation method, is one of the most successful ionisation methods for mass spectrometric analysis and investigation of large molecules.

Maldi-mass spectrometry matrices

Maldi (matrix-assisted laser desorption/ionisation), a laser-based soft ionisation method, is one of the most successful ionisation methods for mass spectrometric analysis and investigation of large molecules. In addition, analysis of post source decay (decay of proteins following the ionisation) in many cases allows rapid sequencing of proteins. Thus Maldi has gained a crucial importance for protein analysis.

Gene Arrays

Panorama gene arrays provide a semi-quantitative platform for analysis of the expression of hundreds of genes in a single experiment.

Mammalian Genomic DNA Purification Kit

The Sigma GenElute Mammalian Genomic DNA Purification Kit provides a simple and convenient way to isolate pure high molecular weight DNA from a variety of mammalian sources.

News

Sigma-Aldrich Corporation opens European headquarters

Sigma-Aldrich Corporation has opened its European Regional Headquarters in St Gallen, Switzerland.

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