Shimadzu LC/MS/MS method packages

Tuesday, 09 July, 2013 | Supplied by: Shimadzu Scientific Instruments (Oceania) Pty Ltd

Shimadzu LC/MS/MS method packages

Shimadzu has released three method packages for LC/MS/MS. Each includes optimised MRM transitions and collision energies for the compounds of interest, plus LC separation conditions with retention times, spectral libraries and report files. Sample preparation protocols are included for each application.

The LC/MS/MS Rapid Toxicology Screening System includes method parameters for 106 important toxicological compounds, including drugs of abuse, pharmaceuticals, psychotropics and hypnotics. It incorporates established calibration curves and uses diazepam d5 as an internal standard. As a result, the screening tool provides laboratories with the ability to perform semi-quantitative analysis without purchasing dozens of standards. Also included is an optimised sample-preparation protocol for toxicology screening based on QuEChERS, providing a total solution for toxicology screening from sample preparation to reporting.

The LC/MS/MS Method Package for Primary Metabolites is designed for the simultaneous analysis of a variety of metabolites associated with central metabolic pathways. The package allows simultaneous analysis of a wide range of compounds, permitting high-throughput simultaneous analysis of 55 primary metabolites in a single 20 min injection. The compound panel includes primary metabolites associated with the glycolytic system, the TCA cycle and the pentose phosphate pathway, as well as amino acids and nucleotides. The package includes biological tissue sample preparation protocols that are applicable to LC/MS/MS.

The LC/MS/MS Method Package for Lipid Mediators enables high-throughput profile analysis in the study of lifestyle-related diseases. The package is designed for profiling analysis in various biological samples. It provides a solution for the simultaneous analysis of 130 lipid mediators and related compounds ranging from high to low polarities. Chromatographic separation, MRM parameters, preparation techniques and internal standard assignments are included, saving the effort of LCMS method development. Rapid 15 ms polarity switching enables multiple classes of analytes to be analysed in a single run without compromising data quality.

Online: www.shimadzu.com.au
Phone: 02 9684 4200
Related Products

Yokogawa CQ1 benchtop high-throughput 3D confocal imager

The Yokogawa CQ1 benchtop high-throughput 3D confocal imager enables 3D imaging and...

Luxendo InVi SPIM Lattice Pro light sheet microscope for live cell imaging

The Luxendo InVi SPIM Lattice Pro light sheet microscope provides a high level of flexibility for...

Jenoptik ProgRes GRYPHAX NAOS 20 MP colour microscopy camera

Specimens can be displayed with up to 30 fps at 5 MP and captured with up to 20 MP resolution....


  • All content Copyright © 2024 Westwick-Farrow Pty Ltd