Dionex MAbPac SCX-10 column

The MAbPac SCX-10 column has been designed specifically for the high-resolution, high-efficiency analysis of monoclonal antibodies and associated variants.

The column’s non-porous pellicular resin provides high resolving power, permitting the separation of monoclonal antibody variants that differ by as little as one charged residue. Hydrophobic interactions with the resin are eliminated for very efficient peaks. The column is designed to address the regulatory requirements for biopharmaceutical characterisation.

The column, a strong cation exchange column, is complementary to the ProPac WCX-10 column for monoclonal antibody variant analysis, offering an alternative selectivity, and will provide higher resolution and efficiency for variant analysis of some monoclonal antibody samples than the ProPac WCX-10 column.

The latest column is suitable for the high-resolution, high-efficiency analysis of monoclonal antibodies and associated variants and is available in 4 x 250 mm format.