Biotage Isolera Spektra flash purification software

Biotage has announced the launch of an updated version of its Isolera Spektra software with improvements to the time- and solvent-saving step-gradient optimisation feature. The updated software uses TLC data from two to 10 different TLC runs to estimate where the individual sample components will elute, the percentage of strong solvent required and which cartridge is best capable of purifying the amount of sample to be purified.

The technology helps chemists to tailor the purification to separate and purify between one and six compounds in the sample or even target one specific compound of interest, which can reduce purification costs 60% or more over conventional, non-compound specific linear gradients. Furthermore, the simplicity of the software makes it easy for even inexperienced users to take advantage of sophisticated purification strategies.

The launch of the Biotage Isolera Spektra in 2012 moved one-dimensional flash into 2D and 3D with a purification system capable of targeting specific compounds in complex mixtures and even detecting the presence of normally invisible impurities beneath peaks of interest. The latest update extends the step-gradient application range to include the high-capacity Biotage SNAP Ultra and Biotage ZIP Sphere cartridges.