Lonza PowerCHO Advance Media

Lonza has launched PowerCHO Advance Media, the latest addition to the company’s range of specialised, chemically defined, serum-free media for culturing Chinese hamster ovary (CHO) cells.

The media line offers easy filterability, improved cell-growth promotion and high protein titres. In addition to being hydrolysate-free, serum-free and of non-animal origin, the media offerings are enhanced to better support high-density CHO cells in suspension. For therapeutic bioprocessing applications, the medium also facilitates both downstream purification and regulatory compliance.

The media allow for easy scalability, so users do not need to change to a new medium as they progress from research projects through to large-scale production. The medium is also fully chemically defined, which eases the regulatory process when transitioning from research into clinical trials and US FDA submission.

The balanced formulation allows users to maintain high viability (greater than 90%), even at high cell densities, and is said to provide higher protein titre when compared with other media formulations on the market. The cell culture media can be used throughout the research process and beyond.

Originally published here.