Beckman Coulter Life Sciences Echo 525 acoustic liquid handler

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The Beckman Coulter Life Sciences Echo 525 acoustic liquid handler is a modern platform for tipless small-volume dispensing that is designed for use in biochemistry and genomics applications. Liquid transfer is achieved via acoustic droplet ejection (ADE), which uses focused ultrasonic energy to eject small droplets of a defined volume (25 nL for the Echo 525) from a source well into a destination well. This allows rapid, precise liquid transfer at nanolitre to microlitre scales while avoiding tip-based cross-contamination and reducing plastic waste.

The product can assemble a full 384-well plate of qPCR reactions in less than 10 min and is thus suitable for high-throughput qPCR reaction set-up. Luna qPCR reagents from NEB are compatible with Echo-mediated acoustic transfer and maintain sensitive detection and linear quantitation in 384-well format at reduced reaction volumes. In addition, using the Luna Cell Ready One Step RT-qPCR Kit, Beckman Coulter Life Sciences presents a convenient workflow for automated direct RT-qPCR analysis of cell samples, with cell culture and lysis in Echo-qualified source plates providing transfer-ready template lysates for ADE-mediated reaction assembly and high-throughput RT-qPCR analysis.

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