InProcess-LSP NanoFlowSizer nanoparticle sizer
ATA Scientific has announced that it has entered a partnership with InProcess-LSP, innovator of a new inline nanoparticle sizer — the NanoFlowSizer.
One of the greatest challenges in bringing new nanomedicines to the market is determining their particle size during manufacturing. Nanoparticle size control is paramount in the entire process of nanoparticle production, as function, safety and efficacy, particularly for pharma applications, is highly dependent on these properties.
Currently, nanoparticle size is determined through ubiquitous offline methods like dynamic light scattering (DLS). Samples taken from ongoing processes are usually high-concentration nanosuspensions which require dilution prior to analysis. Consequently, these offline measurements can cause production delays and require laborious, expensive, complex and error-prone sample handling.
The NanoFlowSizer is expected to make a significant contribution to improving the performance of entire nanoparticle manufacturing processes from initial R&D to quality phase.
The product offers a non-invasive, online approach that can measure particle size distributions (PSDs) of undiluted, highly turbid nanosuspensions, in process and in flow. The novel process analytical tool is based on spatially resolved dynamic light scattering (SR-DLS) technology. The spatial resolution allows automated selection of information-rich single scattered light from strongly scattering turbid nanosuspensions.
NanoFlowSizer can continuously monitor particle formation and determine the size and polydispersity index (PDI) at any point during particle synthesis. Importantly, the quality, purity and particle size characteristics can be quickly monitored (every 10 s), allowing for in-depth interpretation, understanding and continuous improvement of processes.
Able to be installed for inline, online and offline operation, the NanoFlowSizer offers several benefits in nanoparticle research and development, industrial processing and quality control environments.
For more information: https://www.atascientific.com.au/products/nanoflowsizer/.
Phone: 02 9541 3500
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