Biopharmaceutical filtration

Monday, 20 June, 2005 | Supplied by: http://www.millipore.com/


The Pod platform is an innovative filter system for normal flow clarification and prefiltration applications. Designed for greater process flexibility and productivity, the disposable technology improves process speed, safety and economies in the manufacturing of biopharmaceuticals.

The Pod platform consists of an expandable holder and modular filters that overcome many operational limitations of traditional stainless steel housings. Developed as a self-contained device, each Pod is a single-use filter that reduces the need for clean-in-place (CIP) procedures. This minimises costs associated with water usage and cleaning.

The design not only protects operators from exposure to process fluids, but also allows the units to be drained before change-out for lighter devices that are easier to move. In addition, the design and construction of the Pods can reduce hold-up volume from 40-73% over typical configurations of lenticular discs, providing an increase in product yield.

The modular Pod platform delivers process scalability and flexibility. Without changing hardware, users can run the system in serial or parallel configurations to meet specific process and batch size requirements of 20 to 12,000 L. The small footprint saves floor space and the lightweight design eliminates the need for hoists or high ceiling heights. In addition, the holder is on casters for easy assembly and movement.

Pods are available now with Millistak+ HC media for use in primary and secondary clarification processes.

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