Merck Mobius biopharmaceutical manufacturing products

Friday, 29 April, 2016 | Supplied by: Merck Pty Ltd

Merck is launching three Mobius products that deliver improved efficiency and ease of use for biopharmaceutical manufacturing workflows. The products include a 1000 L single-use bioreactor, a 2000 L mixing system for difficult-to-mix biopharm ingredients and a large-volume liquid transport system for aseptic and non-aseptic substances.

The Mobius 1000 L single-use bioreactor completes the comprehensive Mobius stirred tank portfolio of 3 to 2000 L sizes, delivering greater flexibility and continuity for scale-up. With a bottom-loading drawer for easy and safe bag installation, the bioreactor is designed to achieve homogenous and fast mixing for consistent performance, especially at large scale.

The Mobius Power MIX 2000 creates a strong vortex to handle difficult-to-mix buffers, media and other biopharm ingredients. Powerful mixing is achieved from an impeller design and motor based on magnetically coupled NovAseptic technology, a suitable mixing technology for stainless steel tanks. The product provides accessible, sterile zero deadleg sampling directly from the mixing container. A Probe Port allows insertion of either a re-usable standard probe for non-aseptic processes or a pre-sterilised, single-use sensor for in-process pH measurement of aseptic processes.

The Mobius single-use 3D large liquid transportation system’s single-use bags and stainless steel transporter bins facilitate the safe and convenient road transport of aseptic and non-aseptic media, buffers, in-process intermediates and final bulk drug products at cold or ambient temperatures. The system offers four single-use bag assemblies with working volumes of 100 to 500 L. All bags are constructed from PureFlex Plus film with a low extractable profile and gas barrier properties.

Phone: 1800 800 097
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