Shimadzu LH-40 Liquid Handler and FRC-40 Fraction Collector

The Shimadzu LH-40 Liquid Handler and FRC-40 Fraction Collector are designed to significantly improve capabilities and scalability of the Shimadzu Nexera Prep System.

The LH-40 liquid handler can be used both as a fraction collector and an auto-sampler. It enables seamless purity checks through re-injection in order to provide more efficient preparative purification. Up to six FRC-40 fraction collector units can be connected to enable fractionation into up to 3240 10 mm test tubes.

The Nexera Prep Preparative Purification LC System with AI can investigate separation conditions at the analysis scale then select the size of the preparative column based on the purification amount or injection volume and determine the instrument configuration according to the mobile phase flow rate. It can also select the fraction collector and container size according to the target number of fractions and fraction volume.

Other benefits offered by the system include: optimise the separation and fraction conditions for preparative work; re-inject fractions as necessary, perform analysis,and purity check; perform preparative purification analysis based on detection signals from up to four detector channels, to recognise noises and peaks and selectively detect fractionate target peaks (patent applied); sample rescue function to prevent wastage.