Australian researchers find blindness genes

Studies of twins conducted at the Queensland Institute of Medical Research (QIMR) have revealed a number of genes that appear to affect eyesight.

Data was collected from over 1000 pairs of twins, revealing a new gene for myopia (long or short sightedness), new genes affecting glaucoma risk, and a gene that causes optic nerve hypoplasia, which is one of the leading causes of blindness in children.

“One of the major causes of glaucoma is decreased cornea thickness,” said project leader, Dr Stuart MacGregor from QIMR’s Genetics and Population Health Division

“Our research is the first to identify a gene that influences cornea thickness.”

The team also investigated the relationship between intraocular pressure and glaucoma, and discovered a number of genes that influence the pressure in the eye.

“This type of work can lead to genetic tests that can analyse the risk of blindness, and help doctors to monitor people who may have a higher risk of conditions such as glaucoma,” MacGregor said.

The findings were part of an international study in collaboration with Professor David Mackey’s research team from the Centre for Eye Research Australia.

Meanwhile, the QIMR was last week inducted into the Queensland Business Leaders Hall of fame.

Governor of Queensland Penelope Wensley presented the award to Professor John Hay AC, Chair of QIMR Council, at a ceremony held at the Plaza Ballroom, Brisbane and Convention Centre. An initiative of QUT’s School of Business, the State Library of Queensland and the Queensland Library Foundation, the Hall of Fame celebrates leading businesses and business leaders who have enhanced the state’s reputation and its economy.

“QIMR’s induction is in recognition of a distinguished contribution to community wellbeing through world-class medical research and commercialisation,” said professor Hay upon receiving the award.