Mesoblast targets AMD and retinopathy

By Dylan Bushell-Embling
Thursday, 10 July, 2008

Mesoblast [ASX: MSB] today released results from its sister company Angioblast's pre-clinical trials into using adult stem cells to treat ocular diseases association with abnormal blood vessels.

Trials involving 42 non-human primates indicates that an injection of Mesoblast's proprietary adult stem cells combined with an anti-VEGF agent were able to reduce the number of leaking blood vessels - a major cause of ocular disease - more effectively than using an anti-VEGF agent alone.

The combination also reduced the number of subsequent anti-VEGF injections required in the primates.

The results of this trial will comprise part of the company's IND application to the US FDA.

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