NeuroDiscovery has teeth

NeuroDiscovery [ASX: NDL] has completed two parallel Phase IIa clinical trials of its NSL-101 pain treatment in dental surgery, but only produced one set of reliable results.

NSL-101 was found to be an effective pain masker in patients undergoing the painful dental surgery known as root planing and scaling.

The treatment measured up to the gold standard of local anaesthetic gel, with the added advantage of no adverse side-effects, the company said.

These results are so promising NeuroDiscovery has filed a new patent for NSL-101 as a dental surgery treatment.

But in the second trial, in which patients treated with NSL-101 were measured against a placebo group following wisdom teeth removal, unexpected factors invalidated the results.

NeuroDiscovery did not anticipate how long the local anaesthetic administered during the wisdom teeth procedure would last, and feels the effects of the anaesthetic could have been masking the effects of NSL-101.