Cytiva Xcellerex Automated Perfusion System (APS)

Cytiva’s Xcellerex Automated Perfusion System (APS) is designed to support the biotech industry’s move to continuous manufacturing, simplifying processes and reducing risk when intensifying upstream operations.

In cell cultivation using perfusion, media is continuously fed and product harvested. This increases output compared to traditional batch or fed batch methods, yet perfusion processes still involve substantial manual work and risk. Overcoming this challenge by simplifying and automating upstream operations would alleviate bottlenecks further along the perfusion process, increasing overall productivity and output.

Xcellerex APS integrates with Cytiva’s Xcellerex XDR bioreactors for continuous upstream bioprocessing operations. The system’s automation capabilities include automated filter switching, liquid management and cell bleed, reducing risk for human error and increasing process robustness.