Thermo Fisher Scientific Ion Torrent Genexus System

Thermo Fisher Scientific’s Ion Torrent Genexus System is a fully integrated, next-generation sequencing (NGS) platform featuring an automated specimen-to-report workflow that delivers results in a single day, enabling a future in which local hospitals can adopt NGS testing.

The system’s ultrafast turnaround time and fully automated workflow are designed to minimise user intervention and the potential for human error. It also requires minimal amounts of tissue sample and can run small batches to deliver a comprehensive report in one day. Together, these features will help molecular pathologists in the future to analyse NGS information in parallel with first-line testing modalities, such as immunohistochemistry (IHC).

The Genexus System includes the Genexus Integrated Sequencer, the Genexus Purification System and onboard reporting software. Laboratories can scale their sequencing runs with an innovative sequencing chip design that will enable in-house sequencing facilities to process small batches of samples as they arrive at the lab.

The company also introduced its Oncomine Precision Assay, an innovative pan-cancer panel for the Genexus platform that enables comprehensive genomic profiling from formalin-fixed, paraffin-embedded (FFPE) tissue and liquid biopsy samples with a single assay. The product maximises detection of relevant biomarkers, such as EGFR, ALK, KRAS, BRAF, ROS1, NTRK, RET, HER2, ERBB2 and others, via sequencing from FFPE and liquid biopsy samples. When combined with the Genexus System, molecular testing laboratories will be able to generate comprehensive NGS results within the same time frame as single-gene tests.