Microwave synthesis system

The use of microwave energy for controlled heating of small volumes of volatile liquids under pressure has revolutionised organic synthesis reactions in traditional organic R&D as well as drug discovery. Reactions which previously took days to complete now run in minutes and give much higher recovery levels. This allows scientists to perform many more synthetic reactions in a short space of time and then optimise recovery conditions quickly and automatically.

Biotage has included a triple layered safety protocol in its Initiator microwave synthesis system which means the maximum of operator safety possible.

The Initiator system houses the reaction in a completely enclosed reaction chamber for maximum microwave efficiency and operator safety. The system is available as a single station unit for new users with low sample throughput needs and can be upgraded in the field easily with 8 or 60 place robotic sampling facilities for maximum automation.

Vial sizes from 0.2 through to 20 mL capacity can be accommodated and mixed vial sizes and different protocols can be run in an automated sequence making the Initiator suitable for multi-user environments.

The Initiator is a compact device and incorporates a touch screen display for routine operation and does not need a computer.

Owners of the Biotage Initiator can access the Biotage Pathfinder web-based database which acts as a cookbook for organic reaction pathways and allows rapid implementation of this technique for laboratories starting out. A user can search on structure and quickly find proven conditions to act as a starting point for new work.