Multi-angle light scattering detector

The Wyatt Technology miniDawn Treos Multi-Angle Light Scattering (MALS) Detector claims a major advancement in the sensitivity and dynamic range in the measurement of multi-angle light scattering (MALS) for small molecules. It has over twice the signal-to-noise ratio and 100x the dynamic range of the previous generation of Wyatt's miniDawn instruments, allowing the measurement of smaller molecules at lower concentrations.

Each analog signal (one for each of the three angles) is processed by its own digital signal processing (DSP) integrated circuit with 24 bit digital conversion for extremely high signal resolution. In addition, four auxiliary analog inputs (with their own DSP circuits) are available for interfacing to external detectors, such as DRI, UV, PDA, etc. The temperature, laser power and forward monitor signal, which are useful for studying examples that absorb light, are also recorded.

Optional features may be added such as the embedded Comet system, which automatically cleans the flow cell in situ. Just press a button, or schedule cleaning as part of an Astra sample set. The embedded WyattQELS allows simultaneous online measurement of hydrodynamic radius. This improves the resolution of the size distribution measurements by over an order of magnitude compared to batch QELS.

The miniDawn Treos can work seamlessly with all other Wyatt instruments, such as the ViscoStar differential bridge viscometer, via the network or USB interfaces. It has the capability of taking signals from a variety of third-party instruments, such as UV absorption, DRI, IR absorption, evaporative light scattering or photodiode array detectors.