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Bio-Rad anti-ranibizumab antibodies

Bio-Rad Laboratories has launched a range of recombinant monoclonal anti-ranibizumab antibodies that are highly specific for the monoclonal antibody drug ranibizumab (Lucentis) or the complex of ranibizumab with its target, vascular endothelial growth factor A (VEGF-A).

Bio-Rad Laboratories anti-pembrolizumab and anti-nivolumab antibodies

Bio-Rad Laboratories has launched a range of anti-idiotypic antibodies targeting the immune checkpoint inhibitor drugs pembrolizumab (Keytruda) and nivolumab (Opdivo). Anti-pembrolizumab and anti-nivolumab antibodies are designed for use in bioanalytical assays to monitor the drug levels in cancer patients.

Bio-Rad Laboratories anti-vedolizumab antibodies

Bio-Rad's anti-vedolizumab antibodies include four recombinant monoclonal anti-idiotypic antibodies that are highly specific for the humanised IgG1 kappa antibody drug vedolizumab, and are suitable for development of bioanalytical and patient monitoring assays.

Bio-Rad StarBright Blue 520 Fluorescent Secondary Antibodies

Bio-Rad Laboratories has announced the StarBright Blue 520 Fluorescent Secondary Antibodies — fluorescent dye-labelled secondary antibodies for use in multiplex western blotting.

Bio-Rad Laboratories Bio-Plex Pro Human Cytokine Screening Panel 48-plex

The Bio-Plex Pro Human Cytokine Screening Panel 48-plex is a ready-to-use, 96-well kit that delivers analytical performance and data integrity across 48 well-characterised assays that are multiplexed in a single well.

Bio-Rad Laboratories S3e Cell Sorter

The S3e Cell Sorter is an automated cell sorter with real-time monitoring and smart features equipped with up to two lasers and four fluorescence detectors plus forward-scatter and side-scatter detectors. The compact system, with dimensions of only 70 x 65 x 65 cm, includes onboard fluidics and a temperature control system.

Bio-Rad IncRNA Workflow

Bio-Rad Laboratories has announced the IncRNA Workflow, a RT-qPCR workflow that is optimised for highly sensitive and specific quantification of long noncoding RNAs (lncRNAs) for gene expression analysis. The workflow provides a streamlined alternative to RNA-Seq for lncRNA discovery and validation.

Bio-Rad Laboratories ZE5 Cell Analyzer and flow cytometry antibodies

The ZE5 Cell Analyzer is a flow cytometer that gives users the flexibility to run up to 30-parameter experiments and the convenience of an integrated universal sample loader that accommodates any sample tube or plate format.

Bio-Rad Laboratories NGC Fraction Collector

Bio-Rad Laboratories NGC Fraction Collector allows researchers to choose how to collect and when to access their fractions.

Bio-Rad QX200 Droplet Digital PCR (ddPCR) System

The QX200 Droplet Digital PCR (ddPCR) System from Bio-Rad provides absolute quantification of nucleic acids. It is particularly useful for detection of targets in complex backgrounds or for monitoring subtle changes or low nucleic acid abundance not easily detected/quantified with traditional qPCR.

Bio-Rad ChemiDoc MP Imaging System and Starbright fluorescent secondary antibodies

The ChemiDoc MP Imaging System is designed for multiplex fluorescent western blotting. With triplex acquisition, the product can detect up to three proteins simultaneously to gain more data per sample and minimise stripping and reprobing.

Bio-Rad Laboratories Bio-Plex Pro Human Apolipoprotein Panel

The Bio-Plex Pro Human Apolipoprotein Panel allows researchers to rapidly detect and quantify key human apolipoproteins associated with cardiovascular disease, especially within the statin pathway, as well as the biomarker C-reactive protein.

Bio-Rad ZE5 Cell Analyzer

The ZE5 Cell Analyzer is an easy-to-use, high-performance analytical cytometer that will enable users to perform both basic and multiparameter cytometry for a wide range of applications.

Bio-Rad KnowItAll 2017 spectroscopy software

Bio-Rad Laboratories has announced the release of its KnowItAll 2017 spectroscopy software and databases. The release offers an additional 976,000 reference spectra in the KnowItAll Spectral Library.

Bio-Rad ddPCR CHO and E. coli Residual DNA Quantification Kits

The ddPCR CHO Residual DNA Quantification Kit and ddPCR E. coli Residual DNA Quantification Kit allow for direct quantification of host-cell DNA impurities in biopharmaceuticals purified from bacteria (E. coli) or mammalian cells (Chinese hamster ovary) without the need for upfront nucleic acid purification steps.

Bio-Rad Laboratories KnowItAll spectroscopy software

Bio-Rad Laboratories has announced the latest version of its KnowItAll spectroscopy software. One of the key enhancements of the release is Optimized Corrections, a technology that performs a computationally complex set of corrections on all query and reference spectra in a search to find the optimal match between the query and each reference spectrum.

Bio-Rad PrimePCR Assays for model organism genomes

Bio-Rad Laboratories has launched predesigned PrimePCR Assays for six of the most common model organism genomes used for gene expression analysis: rhesus monkey, zebrafish, yeast, cow, rabbit and pig.

Bio-Rad ddPCR KRAS Screening Multiplex Kit

Bio-Rad Laboratories has launched the ddPCR KRAS Screening Multiplex Kit, the latest offering in the company's Droplet Digital PCR line of predesigned, fully wet-lab validated assays. The kit offers improved sensitivity and simultaneous detection of the seven most common KRAS mutations in a single ddPCR experiment.

Bio-Rad CFX Automation System II robotic plate handler

Bio-Rad Laboratories has announced the CFX Automation System II, a robotic plate handler that enables high-throughput, walk-away, real-time PCR automation for all Bio-Rad CFX Real-Time PCR Detection Systems.

Bio Rad ZOE Fluorescent Cell Imager

Bio-Rad Laboratories has announced the ZOE Fluorescent Cell Imager, a cell imaging system that can deliver the power of microscopy in a system that is as easy to use as a tablet. The system includes three fluorescent channels and brightfield to simplify fluorescence imaging for cell culture applications.

Bio-Rad ChemiDoc Touch Imaging System

The ChemiDoc Touch Imaging System, from Bio-Rad, is a complete solution for gel and western blot imaging. The system combines the sensitivity of film with advanced detection technology to determine the best exposure settings for publication-quality western blot images.

Bio Rad SingleShot cell lysis RT-qPCR kits

Bio-Rad Laboratories has announced the launch of a rapid cell lysis kit that allows researchers to obtain reverse transcription quantitative PCR (RT-qPCR) data directly from cultured cells without the need for a separate RNA purification step.

Bio-Rad SsoAdvanced Universal Inhibitor-Tolerant SYBR Green Supermix reagent for qPCR data delivery

Bio-Rad Laboratories has launched the SsoAdvanced Universal Inhibitor-Tolerant SYBR Green Supermix, a solution for obtaining reproducible, optimal-quality qPCR data from challenging samples.

Bio-Rad KnowItAll ATR/IR ID Expert and Raman ID software for IR and Raman spectral identification

The KnowItAll ATR/IR ID Expert and Raman ID Expert provide fast, accurate answers to scientists identifying unknown infrared and Raman spectra.

Bio-Rad TGX FastCast and TGX Stain-Free FastCast acrylamide kits for gel electrophoresis

Bio-Rad Laboratories has launched its TGX FastCast acrylamide and TGX Stain-Free FastCast acrylamide kits, which provide handcast gel users access to the company's TGX gel chemistry.

Bio Rad KnowItAll Informatics System 2013 spectroscopy software

Bio Rad Laboratories has announced the release of KnowItAll Informatics System 2013 spectroscopy software. The software offers comprehensive solutions for spectral analysis, identification, search, data management and reporting.

Bio-Rad Laboratories Geenius HIV 1/2 Confirmatory

The Geenius HIV 1/2 Confirmatory is a complete system that provides unitary HIV-1 and HIV-2 confirmation and differentiation in serum, plasma or whole blood along with automated reading and interpretation of the results - all in less than 30 min.

Bio-Rad Laboratories Hard-Shell 96-well plates

Bio-Rad Laboratories has announced the availability of two 96-well Hard-Shell plates for PCR and real-time PCR (qPCR).

Bio-Rad Laboratories Bio-Plex Pro Human Th17 Cytokine assays

The Bio-Plex Pro Human Th17 Cytokine assays are magnetic bead-based multiplex assays for the simultaneous detection of cytokines in a single experiment, using as little as 12.5 μL of sample.

Bio-Rad Laboratories KnowItAll software version 9.0

Bio-Rad Laboratories has announced an unlimited spectral range and resolution feature in version 9.0 of its KnowItAll software. KnowItAll 9.0 allows users to store spectra in a user database at the precise range and resolution at which each spectrum was measured rather than being forced to conform to a fixed range and resolution for the entire database. As a result, users have more control over their data and can perform more accurate spectral searches that compare experimental spectra to reference databases.

Bio-Rad Laboratories Bio-Plex Pro human and mouse diabetes assays

Bio-Plex Pro human and mouse diabetes assays are magnetic bead-based multiplex assays for the simultaneous detection of multiple diabetes and obesity biomarkers in a single experiment, using as little as 12.5 µL of sample. These assays have been developed to deliver accurate, reproducible measurements with complete flexibility to meet research needs.

Bio-Rad Trans-Blot Turbo blotting system

The Trans-Blot Turbo is a rapid transfer system for Western Blotting that delivers efficient transfer of proteins from PAGE gels to blotting membranes. The flexible design, high-transfer efficiency and higher throughput of the system enables researchers to obtain optimal, reproducible results quickly and easily.

Bio-Rad KnowItAll software version 8.3

Version 8.3 of the KnowItAll software includes AnalyzeIt spectral interpretation applications for IR, Raman and IR polymer compounds. With this release, users can improve spectral interpretations by building the knowledgebase of functional groups and corresponding bands from their own data to use in conjunction with the software’s built-in knowledgebase.

Gel Doc EZ Imager gel documentation system

The Gel Doc EZ Imager is a compact and automated imaging system for capturing publication-quality images with analysed results of electrophoresis gels, with just a push of a button.

Bio-Rad Laboratories SsoFast EvaGreen Supermix qPCR reagent mix

SsoFast EvaGreen Supermix is the first member of Bio-Rad’s next-generation family of high-performance, real-time PCR reagents. Through instant polymerase activation, optimal primer binding and rapid polymerisation kinetics, the supermix is claimed to enable qPCR cycling protocols to be completed in less than 30 min, representing up to a 25% improvement compared to other currently available fast qPCR mixes.

Bio-Rad Mini-PROTEAN Tris-Glycine extended (TGX) precast gels

Mini-PROTEAN Tris-Glycine extended (TGX) precast gels have been developed for protein electrophoresis using the standard Laemmli buffer system. The modification extends the gel shelf life to more than 12 months and can be run to completion in as little as 12 minutes.

Bio-Rad Laboratories Precision Plus Protein Dual Xtra standard

Bio-Rad Laboratories has added the Precision Plus Protein Dual Xtra standard to its Precision Plus Protein line of protein standards: the Precision Plus Protein Dual Xtra standard, which provides 12 reference bands, from 2 kD to 250 kD.

Bio-Rad Laboratories CFX qPCR automation system

The CFX automation system enables walk-away, high-throughput qPCR on Bio-Rad’s CFX96 and CFX384 real-time PCR detection systems.

Bio-Rad Laboratories Precision Plus Protein Dual Xtra standard

Bio-Rad Laboratories has added the Precision Plus Protein Dual Xtra standard to its Precision Plus Protein line of protein standards: the Precision Plus Protein Dual Xtra standard, which provides 12 reference bands, from 2 kD to 250 kD.

Bio-Rad Mini-PROTEAN Tris-Glycine extended (TGX) precast gels

Mini-PROTEAN Tris-Glycine extended (TGX) precast gels have been developed for protein electrophoresis using the standard Laemmli buffer system. The modification extends the gel shelf life to more than 12 months and can be run to completion in as little as 12 minutes.

Bio-Rad Laboratories CFX qPCR automation system

The CFX automation system enables walk-away, high-throughput qPCR on Bio-Rad’s CFX96 and CFX384 real-time PCR detection systems.

Bio-Rad Laboratories SsoFast EvaGreen Supermix qPCR reagent mix

SsoFast EvaGreen Supermix is the the first member of Bio-Rad’s next-generation family of high-performance, real-time PCR reagents. Through instant polymerase activation, optimal primer binding and rapid polymerisation kinetics, the supermix is claimed to enable qPCR cycling protocols to be completed in less than 30 min, representing up to a 25% improvement compared to other currently available fast qPCR mixes.

Bio-Rad Laboratories SsoFast probes supermix

Bio-Rad Laboratories has released SsoFast probes supermix, a reagent which enables researchers using fluorogenic probes to enhance the speed, reliability and sensitivity of their qPCR experiments.

Bio-Rad TC10 automated cell counter

The TC10 automated cell counter accurately and reproducibly provides total mammalian cell counts in 30 s or less - eliminating the need for manually counting cells under the microscope using a haemocytometer.

Bio-Rad BioPlex 2200 Anti-CCP test

Bio-Rad Laboratories and Axis-Shield have launched Bio-Rad’s BioPlex 2200 Anti-CCP test for the early detection of rheumatoid arthritis. The assay, which will run on Bio-Rad’s BioPlex 2200 system, measures anti-CCP (anti-cyclic citrullinated peptide antibodies), a novel marker that has been shown to have superior specificity in the diagnosis of rheumatoid arthritis. The BioPlex 2200 Anti-CCP kit is based on Axis-Shield’s proprietary anti-CCP technology. The assay is available for sale in certain countries outside the US.

Bio-Rad Molecular Imager Gel Doc XR+ System

An emerging trend in molecular biology is the move away from ethidium bromide staining and UV visualisation to the use of optimised fluorescent stains and less harmful illumination.

Infectious disease serology panels

Bio-Rad Laboratories has received FDA clearance of two multiplex infectious disease serology panels for use on the BioPlex 2200 system: the BioPlex ToRC IgG panel and the BioPlex HSV-1 and HSV-2 IgG panel. The BioPlex 2200 system is a fully automated, random access platform that employs multiplexing technology to analyse multiple disease markers from a single patient sample.

Electroporation system cuvette

Bio-Rad Laboratories has launched the Gene Pulser MXcell ShockPod cuvette chamber for its Gene Pulser MXcell electroporation system. The ShockPod offers researchers the flexibility to easily transition between electroporation plates and familiar cuvettes on the Gene Pulser MXcell electroporation system.

Acute phase assays

Bio-Plex Pro human acute phase assays can deliver accurate and reproducible measurements of nine commonly studied acute phase markers: a-2-Macroglobulin, CRP, ferritin, fibrinogen, haptoglobin, procalcitonin, SAA, serum amyloid P (SAP) and tissue plasminogen activator. A snapshot of panel performance is demonstrated by representative parallelism and linearity of sample dilution in normal human serum and plasma.

Human isotyping assay

The Bio-Plex Pro human isotyping panel allows detection of IgG1, IgG2, IgG3, IgG4, IgA, IgE and IgM, in a single multiplex assay.

Cancer biomarkers evaluation

Bio-Rad Laboratories has released a technical note (tech note 5654A) describing the study of an evaluation of cancer biomarkers. In the study, Bio-Rad researchers evaluated the Bio-Plex suspension array system’s ability to detect the levels of nine biomarkers, which were selected for their potential clinical relevance to cancer development. The nine biomarkers: angiopoietin-2 (Ang-2), VEGF, PDGF-BB, leptin, PECAM-1, IL-8, follistatin, HGF and G-CSF were collected in sera from four different types of cancer patients.

Real-time PCR detection system

The Bio-Rad CFX96 real-time PCR detection system features an optical reaction module that builds on the power and flexibility of the C1000 thermal cycler, creating an easy-to-install, real-time PCR system.

Wash stations for xMAP assays

Bio-Rad Laboratories has released two Bio-Plex Pro Wash Stations for washing bead-based assays. The Bio-Plex Pro Wash station is used exclusively for magnetic beads. The Bio-Plex Pro II Wash Station automates magnetic and vacuum wash steps for researchers who use a combination of magnetic and polystyrene assays.

Protein interaction analysis

Bio-Rad Laboratories has released a GLH sensor chip for its ProteOn XPR36 protein interaction array system. The chip generates a high analyte signal through its high ligand activity and binding capacity. The amine coupling chemistry and polymer layer of the GLH sensor chip is similar to the ProteOn GLC and GLM chips, allowing ligand binding across a wide pH range.

Electroporation protocols

Bio-Rad Laboratories has released 12 protocols for electroporation of human primary cells and primary cell lines.

Low-pressure liquid chromatography

The Profinia protein purification system is an automated low-pressure liquid chromatography system that provides researchers a method to perform automated affinity purification and desalting of recombinant tagged proteins.

Supermixes for real-time PCR

The iTaq fast supermixes with ROX can be used on a variety of instruments, including ROD-dependent real-time PCR systems, and are designed to deliver qPCR efficiency, sensitivity and specificity, with a robust fluorescent signal under fast or standard cycling conditions with real-time detection chemistry.

Fusion-tagging system

Profinity eXact fusion-tag system’s purification resin is part of a complete expression and purification system that simplifies affinity purification and tag removal of fusion-tagged proteins, while avoiding adding time and reagent costs to the purification process.

Tetra cell gel electrophoresis

The Mini-Protean Tetra system for vertical mini gel electrophoresis can run up to four mini gels in less than an hour or 2D gels in less than a day.

Infrared databases

Bio-Rad Laboratories has released seven infrared databases including: name of database number of spectra; pharmaceutical excipients 882; biochemicals 590; pollutants (IR vapour phase) 910; flavours and fragrances (IR vapour phase) 496; protective materials 772; acrylates and methacrylates 478; steroids, androgens, progestins and estrogens 305.

Metabolomics research software

Version 7.5 of the KnowItAll Informatics System offers enhancements to many of the applications featured in previous versions of the platform and features a new edition of the software, the KnowItAll Informatics System - Metabolomics Edition for metabolomics research.

Laser scanning microscope software

Bio-Rad Microscopy Division has released an option for users of its LaserSharp2000 Version 4 software. This advancement allows users to perform Multiphase Time Course experiments with Laser Scanning Microscopes. The option will bring advantages in efficiency and quality of results to applications in the areas of cell biology, neurobiology, pharmacology, cell-signalling, etc.

Laser Scanning Microscope

The Radiance2100 confocal and multiphoton microscope can be progressively upgraded from single channel confocal through to multichannel multiphoton systems as required. Confocal microscopy enables the acquisition of optical section images through a fluorescent biological sample so that only light that is in focus is collected.