Beckman Coulter protein characterisation application note
25 May, 2011The application note ‘Assay Of IgG Purity And Heterogeneity Using High-Resolution Sodium Dodecyl Sulfate Capillary Gel Electrophoresis’ highlights the development of both a new polymer formulation and standardised methodology to assess the purity and heterogeneity of IgG and its isoforms.
Odyssey Thera compounding profiling service
20 April, 2011 byUsing cutting-edge Protein-fragment Complementation Assay technology from Odyssey Thera, Lonza is able to offer profiling services that can shape and influence critical decisions about drug candidates.
Innova Biosciences imm-Link Immunogen Linking Kits
20 April, 2011Innova Biosciences imm-Link Immunogen Linking Kits simplify the conjugation of haptens to carrier proteins. Large immune responses are stimulated by BSA, ovalbumin and keyhole limpet hemocyanin (KLH) and are typically used as carrier proteins to generate antibodies against small antigens (eg, peptides or organic compounds - ie the ‘hapten’). To successfully stimulate the production of antibodies, the antigen needs to be covalently linked to a carrier protein.
Lonza GelBond film for agarose gels
22 March, 2011 byGelBond film is a transparent, flexible polyester film designed to support agarose gels.
Location, location, location
02 March, 2011 by Sarah C P WilliamsBiologists readily accept the general principle that location is intricately tied to function. Quantifying this is hard, however.
Bio-Rad Trans-Blot Turbo blotting system
03 February, 2011 byThe Trans-Blot Turbo is a rapid transfer system for Western Blotting that delivers efficient transfer of proteins from PAGE gels to blotting membranes. The flexible design, high-transfer efficiency and higher throughput of the system enables researchers to obtain optimal, reproducible results quickly and easily.
Wyatt Technology Möbiuζ mobility instrument
03 February, 2011
by
Wyatt Technology’s Möbiuζ mobility instrument incorporates several innovations to realise fast and reliable measurements of macromolecular electrophoretic mobilities.
Transmembrane protein characterisation
28 December, 2010 byTransmembrane proteins are key determinants of the pharmacokinetics of drugs and their characterisation is of increasing importance for the pharmaceutical industry.
Tecan and PhyNexus protein purification automation
07 October, 2010 byTecan and PhyNexus have developed standard processes for automating protein purification using PhyTip columns integrated onto a Freedom EVO liquid handling platform. The Freedom EVO is equipped with a liquid handling arm and a MultiChannel Arm and controlled using specially adapted scripts of standard Freedom EVOware operating software.
Computer gamers tackle protein folding
06 September, 2010A cooperative online game that puts volunteer ‘gamers’ to work folding proteins has attracted 50,000 players whose ‘distributed thinking’ has, in some cases, proven more powerful than computers in predicting the three-dimensional structure of proteins.
TTP LabTech LCP liquid handler
04 August, 2010 byTTP LabTech’s mosquito LCP liquid handler is a dedicated device that has been designed to facilitate the crystallisation of membrane proteins, such as G-protein coupled receptors, by offering a fully automated solution to lipid cubic phase (LCP) screening. It incorporates an auto-homing positive displacement syringe for the accurate and repeatable dispensing of LCP in addition to the standard disposable, positive displacement mosquito tips that are claimed to eliminate zero cross-contamination. This novel automation system enables LCP screening to be performed accurately and with ease and increases the throughput of crystallisation set-ups.
Bio-Rad Mini-PROTEAN Tris-Glycine extended (TGX) precast gels
04 August, 2010Mini-PROTEAN Tris-Glycine extended (TGX) precast gels have been developed for protein electrophoresis using the standard Laemmli buffer system. The modification extends the gel shelf life to more than 12 months and can be run to completion in as little as 12 minutes.
Bio-Rad Mini-PROTEAN Tris-Glycine extended (TGX) precast gels
03 August, 2010Mini-PROTEAN Tris-Glycine extended (TGX) precast gels have been developed for protein electrophoresis using the standard Laemmli buffer system. The modification extends the gel shelf life to more than 12 months and can be run to completion in as little as 12 minutes.
Abnova antibody pairs for proximity ligation assay
06 April, 2010 byAbnova offers a range of over 30,000 antibody pairs for proximity ligation assay (PLA). PLA is a technique that allows the immunohistochemical assessment of protein-protein interactions. It involves the binding of a ‘probe’ (ie, a pair of antibodies from two different species attached to DNA probes) to the target protein of interest.
MembranePro Functional Protein Expression System
06 April, 2010 byThe MembranePro Functional Protein Expression System is suitable for users studying GPCRs and other membrane proteins. MembranePro is a ready-to-use system that delivers enriched, functional membrane proteins efficiently and reliably.
