Case Studies
BeiGene chooses CHOZN for oncology drug development
Oncology company BeiGene has purchased SAFC's off-the-shelf, turnkey CHOZN cell line production platform and cell line engineering services to support discovery and commercial development of BeiGene's targeted oncology drug. [ + ]
Biomarker-selected clinical trial supported by RNA detection technology
Merrimack Pharmaceuticals is utilising RNAscope technology, from Advanced Cell Diagnostics (ACD), to select patients for its Phase 2 clinical trial of its product candidate MM-121. [ + ]
Mass spectrometry systems enable sensitivity in drug trials
The International Pharmaceutical Research Center (IPRC) in Jordan is investing in two AB SCIEX Triple Quad 6500 LC/MS/MS systems in order to offer new capabilities for bioanalysis studies of Phase I clinical trial compounds. [ + ]
Novel activity identified for an existing drug
Drug discovery company Re-Pharm has used computational chemistry suite Forge, a product of its parent company Cresset, to identify novel anti-inflammatory activity for an existing drug which is widely prescribed for other non-inflammatory conditions. [ + ]
Sheffield NHS lab is sure about CytoSure arrays
Following a highly stringent National Health Service (NHS) tender for the supply of oligo-based cytogenetics research arrays, Sheffield Children's NHS Foundation Trust has seamlessly transferred to the CytoSure ISCA 8x60k platform from Oxford Gene Technology (OGT). [ + ]
Temperature monitoring of frozen embryos, sperm and ova
Testo's automated temperature monitoring system - Saveris - is used by IVF Australia to ensure the safe storage of frozen embryos, sperm and ova. [ + ]
DNA, RNA and protein extraction from skin tissue
Effective, efficient sample preparation is critical to successful downstream results. Now an effective method exists for the extraction of intact, biologically functional macromolecules from skin. [ + ]
Automated purification of high-quality genomic DNA
The Eppendorf epMotion M5073 with MagSep Tissue gDNA kit is an efficient and effective way of isolating genomic DNA in an automated environment. [ + ]
Rapid and thorough DNA, RNA and protein extraction
The FastPrep-24 5G high-speed benchtop homogeniser is an ultrahigh-performance sample preparation system that allows for the extraction of fully intact, biologically functional macromolecules from routine as well as highly resistant samples. [ + ]
MicroRNA profiling
As microRNA (miRNA)-based research shifts from discovery of new miRNAs to elucidating their biological roles and their utility as biomarkers, robust methods are needed to profile large sample cohorts. [ + ]
