Liquid chromatography solvents

Reproducible HPLC separations require solvents to have a high degree of UV transmittance, low particle count, low acidity and alkalinity and a low level of evaporation residue. Merck’s LiChrosolv solvents meet these requirements; they are produced from specially selected raw materials and undergo a number of purification steps before final packaging.

Other benefits of the HPLC LiChrosolv range include batch-to-batch consistency, documented suitability for UV analysis, fluorescence and mass detection.

In analytical HPLC, separations are normally carried out under gradient conditions. Because of this, solvents are available in ‘gradient grade’ as well as in ‘isocratic grade’.

In Australian and New Zealand, LiChrosolv HPLC solvents are supplied in 1, 2.5 and 4 L glass bottles and 5 L aluminium bottles.

The glass bottles feature optimum characteristics for handling, storage and transport; safe footprint; low centre of gravity; safety screw cap — S50 (polypropylene) with a circlip as an originality device and PTFE-insert for optimum closeness; and high pressure resistance.

To comply with transport regulations the glass bottles must be protected by pads of polystyrene. Such polystyrene packages are dispatched as packages of 6 x 1 L or 4 x 2.5 L in a special folding corrugated cardboard box that has been approved for transport purposes.