MBF Bioscience Vesselucida 360 microvasculature imaging software

MBF Bioscience’s Vesselucida 360 software enables automatic reconstruction and quantitative analysis of microvasculature. The latest software version includes capabilities that empower researchers studying neurodegeneration, TBI, stroke, angiogenesis in cancer, diabetic retinopathy and other conditions that affect microvasculature.

The software is designed to accurately segment and fully reconstruct vessels and microvasculature in 3D, enabling users to obtain data about vascular length, connections, loops, and complexity of vessels and microvessels from small or large 3D images. It works on vessels in any species from a variety of labelling and microscopy techniques, such as immunofluorescence, immunohistochemistry, animal models with fluorescent reporters, lectin perfusion, brightfield, widefield fluorescence, confocal, light sheet, 2-photon, multi-photon, micro-CT, whole brain or organ, cleared tissue, sectioned tissue, cultures and expanded tissue.

Expanded file support means the software now supports saving image crops in .tif format and opening DICOM (.dcm) images, providing greater flexibility for data management. The Image Scaling dialogue box, appearing when opening images, also features updated and more helpful information for a smoother workflow. Other benefits include enhanced 3D object display and streamlined automatic tracing, as well as refined puncta detection and improved batch processing.