BD and Cellular Research jointly promote single-cell sequencing products

BD Life Sciences, a segment of medical technology company BD, is teaming up with biotechnology company Cellular Research to jointly promote the businesses’ solutions for highly multiplexed cell isolation and single-cell gene expression analysis. The companies are offering users an integrated workflow for measuring both nucleic acid and protein expression in cellular subtypes.

Cellular Research’s Precise is a highly multiplexed molecular and sample barcoding technology whereby each transcript in each plated cell is uniquely barcoded during incorporation into one sequencing library. Precise encoding plates can also be multiplexed, enabling up to 4608 single cells to be prepared into one single sequencing library and reaction. Cells can be individually sorted into 96- or 384-well encoding plates using the powerful BD FACS instruments and software.

Cellular Research CEO Dr Stephen Fodor said the combination of capabilities will “significantly increase the ability to identify and analyse cell populations for basic and clinical research”. BD Biosciences Worldwide President Claude Dartiguelongue added that the announcement represents “an exciting step forward for researchers engaged in single-cell genomic analysis”.

“The efficiency of identifying and isolating single cells greatly increases the throughput of cells available for transcriptome analysis, creating the potential, now within reach of investigators, to analyse gene expression targets in many thousands of individual cells,” Dartiguelongue said.

Initial results and findings were presented during the 16th annual Advances in Genome Biology and Technology (AGBT) meeting, held in Florida from 25-28 February.

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