GenTegraRNA-NEO Active Chemical Protection technology for microsampling

GenTegraRNA-NEO Active Chemical Protection technology, designed exclusively for Trajan Scientific and Medical, can be applied to Trajan’s Neoteryx Mitra microsampling devices based on VAMS technology for RNA-based studies. Once treated, the devices are intended to provide researchers with high-quality RNA recovery from remote blood microsamples that don’t require cold shipping or storage for up to seven days before extraction.

The technology protects against naturally occurring nucleases and environmental stresses that could degrade the RNA in blood samples. Not only does it safeguard RNA integrity in dried blood, it also opens new avenues for RNA-based research by enabling convenient, non-invasive blood collection methods.

The technology has been developed specifically for use with the absorbent VAMS tips on Mitra devices before blood sample collection. The pre-treated devices can be used by research staff or laypersons and are intended to expand access to remote study cohorts for RNA-based research and molecular studies by replacing phlebotomy with easy finger-stick blood collection at home or in a clinic setting. The devices may be applied in a range of research projects, including studies in miRNA and mRNA therapy development, biomarker discovery, pharmacogenomics, transcriptomics and other omics studies, and clinical trial screening, among others.

The treated devices are designed to offer ease and precision via a volumetric absorptive microsampling method. The ‘micro-sized’ sample volumes can enable research not possible with standard blood collection techniques, including sampling among vulnerable populations and field research in remote locations where cold storage or specialised shipping are not available. After collection, Mitra microsamples are shipped and stored as dried blood samples, ready for RNA extraction in a lab within seven days.