GeneCopoeia HDR donor clones

Monday, 25 July, 2016 | Supplied by: United Bioresearch Products Pty Ltd

Homology-directed repair (HDR) is a natural DNA repair mechanism that is induced by DNA double-strand breaks (DSBs). Site-specific TALENs or CRISPR Cas9-sgRNA complexes generate DSBs in the chromosome, leading to DNA repair. In the presence of donor DNA, HDR occurs and replaces genetic information in the chromosome with information from the donor.

GeneCopoeia HDR donor clones and cloning vectors enable many CRISPR applications, such as precisely defined gene knockout, in-frame fusion tagging, transgene insertion and the introduction of base pair changes for mutagenesis or disease correction.

For more information:

Phone: 02 4575 0309
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