Lonza Human Diabesity 384 StellARray qPCR Array

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The Human Diabesity 384 StellARray qPCR Array can be used to profile the expression pattern of genes that have been identified as important in diabetes and obesity research. Users can perform an extensive gene expression profile of Type 2 diabetes and obesity.

Users can measure genes involved in many metabolic pathways, such as insulin signalling and secretion, AMPK signalling, fatty acid and lipid metabolism, glycolysis and gluconeogenesis, PPAR-gamma signalling, adipocytokine signalling and other important genes that regulate energy metabolism.

Also included is the ability to measure polymorphic genes that have been identified through association studies and targeted mutations in mice.

Other genes include those that encode protein hormones that participate in the regulation of appetite, storage patterns of adipose tissue, development of insulin resistance and important pro-inflammatory markers that are precursors of metabolic syndrome.

Primer pairs are designed to detect both RNA (as cDNA) and genomic DNA in separate assays - this enables analysis of both gene expression and genomic DNA copy-number variations (CNV) derived from the same primer pairs.

The assay is wet lab validated and selected to yield single peak melt curves. Strict manufacturing QA/QC procedures ensure consistency of performance.