ETD for protein and peptide analysis
Thursday, 26 April, 2007
ETD for protein and peptide analysis
Thermo Fisher Scientific has released the LTQ XL linear ion trap mass spectrometer equipped with electron transfer dissociation (ETD).
This ion fragmentation technology provides important new peptide structure information not available from conventional dissociation methods.
The addition of ETD to the LTQ XL linear ion trap mass spectrometer provides significant advantages for protein/peptide characterisation, post-translational modification (PTM) analysis and top-down or middle-down sequencing of proteins and peptides.
ETD technology takes advantage of the huge ion storage capacity and fast cycle times of linear ion trap technology, allowing researchers to conduct rapid, alternating collisionally induced dissociation (CID) and ETD scanning throughout the LC/MS analysis of complex samples, in a way that is not possible on three-dimensional ion traps.
A new version of BioWorks software streamlines the processing of ETD data. CID and ETD spectra are searched independently, with results from both searches combined for easy comparison and sorting.
This new system provides the most complete view of a proteome possible.
Thermo Fisher Scientific
Tel: 0419 403 547
www.thermo.com
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