Unravelling the haplotype

The ambitious HapMap project is attempting to divine a haplotype map of the human genome. If it's successful, it could be a tremendous resource to researchers trying to identify gene variants affecting health. But not everyone is convinced the HapMap project is going about its endeavour the right way. Malcom Simons is one. Simons has a different view about how to separate the haplomic knot, and he talks to Graeme O'Neill about it in our cover feature in this issue.

We also speak to Lyn Griffiths about her fascinating research with the founder population on Norfolk Island - including descendants of the Bounty mutineers - to uncover the genes involved in migraine. Fiona Wylie looks at David Booth's work investigating the causes and pathogenesis of MS.

Biochemistry is also on the cards, with a look at the work of Mark von Itzstein - of Relenza fame - on keeping ahead of influenza and Jamie Rossjohn's insights into the inner workings of the immune system.

Clinical research and clinical trials are also under the spotlight, with a profile of Ross Andrews pionnering work in giving vaccinations to pregnant women in the Top End and a look at the up-and-coming ChemGenex, which is on the cusp of launching its targeted leukaemia therapy in the US and Europe.

Plus, there's the usual events listings, a sneak peak at newly released books and the ubiquitous LabNews, showcasing the latest in new products.

Also, don't miss our READERSHIP SURVEY. Tell us what you think about Australian Life Scientist, and you could win yourself a case of Australian wine delivered to your door!

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