Precision Nanosystems NanoAssemblr Benchtop for rapid manufacture of nanoparticles

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Current nanoparticle manufacturing methods can be sensitive to reaction conditions, difficult to reproduce, labour intensive and challenging to scale. The automated NanoAssemblr Benchtop is designed to solve these significant issues and allow scientists to accelerate the discovery and development of novel nanomedicines from bench to clinic.

The NanoAssemblr technology is designed for fast and controlled molecular self-assembly of nanoparticles (~20 to 120+ nm) at nanolitre scale (<20 nL) through the use of highly engineered microfluidic mixing cartridges. Formulation runs require less than a minute therefore more than 30 formulations can be completed in a day for rapid optimisation. Fast mixing (<3 ms) on a small scale allows reproducible control over particle formation, resulting in consistent particle populations with low polydispersities.

Nanoparticles can be engineered with defined characteristics including chemical composition, drug/component ratio and drug/component concentrations. Small molecules, peptides and nucleic acids can be formulated into lipid, polymer or hybrid nanoparticles and more.

Applications include: protein delivery and screening, nucleic acid delivery and screening, nanoparticle design, targeted drug delivery, lipid nanoparticles, liposomes and polymeric nanoparticles.

For more information: https://www.atascientific.com.au/products/nanoassemblr-benchtop/.