Full bacterial genome assembly on the desktop with Geneious Pro 5.0
Tuesday, 08 June, 2010
New Zealand science software specialists Biomatters has released the latest version of its Geneious Pro sequence analysis software, which it says will allow users to achieve the full bacterial genome assembly for data from a range of leading sequencers using just a desktop computer.
Geneious 5.0 also features a number of analysis tools for the detection of mutations, repeat finding as well as a new split-screen viewer enabling researchers to open multiple different views of the same sequence. Ease of use is enhanced by improved features for visualising, browsing and analysing large data volumes.
The company notes that the ‘variation finder’ is able to detect all mutations in a novel bacterial strain by comparing it to an ancestral strain using the reference assembly method, to determine the underlying genetics of its phenotype.
The split screen viewer allows for easier navigation of the genome by these annotations, as well as supporting ‘in silico’ cloning and restriction analyses.
"Geneious has several capabilities that have really simplified and sped up my data analysis and interpretation. I can now move fluidly from primer design, to sequence assembly, to analysis within one platform,” said Dr. Sher Hendrickson of the National Cancer Institute, who beta-tested the software. “The new Sequencer contig import option in Geneious Pro 5.0 also allowed me to recover years of prior analyses with little problem”.
Biomatters is offering a 14-day free trial of Geneious Pro, downloadable at www.geneious.com.
The company also announced that it is beta testing a new software solution called Geneious Server with a small number of institutions. It is designed to enable users to offload CPU-intensive tasks like next-generation sequencing, phylogenetics and sequence analysis to servers and supercomputers in other locations to increase the speed of these operations.
Geneious is licensed to more than 1500 research institutes around the world, including all of the world’s 25 top universities, Biomatters said.
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