Daicel chiral HPLC columns

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Daicel chiral columns are claimed to be the most referenced chiral HPLC columns. Used for their high quality, broad selectivity and high loading capacities, they separate >99% of all racemic compounds.

The company’s immobilised columns (ChiralPak IA, IB, IC, ID, IE, IF) are designed for solvent flexibility for the resolution of compounds with limited solubility, good solvent tolerance and good separations of enantiomers.

Its normal-phase HPLC (ChiralPak AD, AS, AY, AZ; ChiralCel OD, OJ, OX, OZ+) chiral stationary phases (CSPs) are widely used for chiral separation. More than 80% of enantiomers can be separated with the polysaccharide-based chiral columns. They are available in semi-micro to preparative type.

CROWNPAK columns are reference columns for achieving amino acid separations, with the advantage that the elution order of the enantiomers can be reversed when necessary. The CR(-) column gives the reversed elution order compared to the CR(+) column.

The Q Series columns are enantioselective weak anion-exchange (AX) HPLC columns. They are designed specifically for enantioselective HPLC of chiral acids and possess good enantiomer separation capabilities for acidic chiral compounds containing carboxylic, phosphoric or sulfonic acid groups.

Other column types for special applications include supercritical fluid chromatography columns, ligand exchange and polymethacrylate chiral stationary phases.