Oxford Nanoimaging (ONI) Nanoimager super-resolution fluorescence microscope

Oxford Nanoimaging (ONI) has released the Nanoimager, a super-resolution fluorescence microscope capable of single-molecule imaging.

The Nanoimager is an elegant yet robust bespoke platform that is said to simplify and increase the efficiency of fluorescence imaging, providing levels of detail not previously possible. This provides researchers with more information about the ultrastructure of cells and the interactions and dynamics of single molecules. It is suitable for research in biology, streamlining the development of novel assays and sensors.

The product offers established single-molecule localisation microscopy methods such as d-STORM and PALM, which are capable of imaging at high temporal resolution. This enables users to capture super-resolution images that routinely demonstrate sub 20 nm resolution, making it suitable for researchers working in areas such as cell biology, protein assemblies, epigenetic mapping, exosomes and microvesicles.

The simple design eliminates the need for optical benches and vibration damping and allows the system to be placed into any laboratory setting. The resultant compact size and desktop form factor enable the unit to have minimal drift. The optimised closed microscope design also reduces maintenance, while providing high throughput levels and automation.