Phenomenex Aeris core-shell HPLC/UHPLC columns

The Phenomenex Aeris core-shell HPLC/UHPLC columns have been specially designed for the analysis of proteins and peptides. The high-performance columns are claimed will deliver higher resolution and peak capacities than other bioseparation media, producing sub-2 micron results on any LC instrument. With virtually no bleed, Aeris columns are highly compatible with MS.

Aeris columns are offered in wide- and small-pore configurations. The Widepore 3.6-micron core-shell columns are optimised for the separation of intact proteins and polypeptides, and are available in three selectivities - XB-C18, XB-C8 and C4. Because the 3.6-micron core-shell particles produce lower backpressures than traditional media, longer or coupled columns can be used to increase resolving power on both HPLC and UHPLC instruments.

Aeris Peptide 3.6-micron and 1.7-micron columns, designed with a small pore size, are recommended for the separation of low molecular weight peptides and for peptide mapping. The XB-C18 stationary phase provides suitable surface chemistry for resolving peptides. Peptide 3.6-micron particles offer ultra-high performance at backpressures compatible with both HPLC and UHPLC instruments. On UHPLC systems, the 1.7-micron Aeris particles can deliver higher peak capacities than fully porous sub-2 micron columns.

The Aeris columns are plug and play, requiring very little work in method transfer.