Active Motif spike-in controls

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Variations across data may obscure true differences between samples in ATAC-Seq, CUT&RUN or CUT&Tag assays. Active Motif has now developed, validated and published spike-in reagents for ChIP-Seq, and has introduced this valuable tool for ATAC-Seq, CUT&RUN, CUT&Tag and CUT&Tag R-loop assays. Now variation between datasets can be normalised to enable sample comparison and reveal true biological differences.

With spike-in normalisation control, scientists can compare datasets between samples in ATAC-Seq, CUT&RUN or CUT&Tag assays. Users simply need to add spike-in nuclei to their samples and perform the assay together in one reaction — this will enable them to obtain the normalisation factor and reveal the true differences between samples.

For further information, contact United Bioresearch Products, the distributor of the full Active Motif range in Australia, or visit https://www.activemotif.com/catalog/1384/spike-in-normalization.

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