Ebers Medical tissue engineering bioreactors

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Ebers Medical develops, manufactures and commercialises devices for research in cell culture with special emphasis in the field of bioreactors and culture chambers for tissue engineering. The bioreactors are used to reproduce in an in vitro culture environment some of the conditions which cells experience when growing in vivo by using two different approaches: the application of controlled flow rates or the direct deformation of the scaffolds in which cells are seeded.

The TEB1000 Master Unit is able to substitute equipment frequently used for cell culture in tissue engineering such as CO₂ incubators, peristaltic pumps and heaters. The system incorporates these features along with CO₂ and O₂ concentration control, allowing a wide variety of experimental set-ups. Controlled flow profiles creating perfusion or perifusion flows for cell seeding and stimulation experiments and creation of hypoxic conditions are all possible.

Ebers culture chambers allow researchers to culture cells on porous bone-type scaffolds as well as on cylindrical vessel-type scaffolds. The TC-3 bioreactor allows application of direct compression on the scaffolds to simulate in the culture the deformation occurring in the in vivo tissues. Tension and compression can be alternatively applied to simulate the growing conditions in ligament, tendon or bone scaffolds.

Adaptation of bioreactors and culture chambers to the particular demands of applications is also available.