Beckman Coulter GenomeLab GeXP Genetic Analysis System

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The GenomeLab GeXP Genetic Analysis System can be used to multiplex up to 30 genes in one reaction, quantitatively and reproducibly, using only a small amount of RNA sample.

The highly multiplexed reverse transcription PCR approach (XP-PCR) quickly and efficiently looks at the expression of multiplexed gene sets with greater sensitivity, speed and cost effectiveness compared to single and multiplex based-q PCR approaches.

The system can accurately detect as low as 0.5-fold changes in gene expression, providing more precise information. Powered with the universal priming strategy, XP-PCR allows multiple reference genes, genes of interest and an internal control to be unbiasedly analysed in a single well. This enables the most accurate normalisation and leads to reliable detection of very small changes in gene expression.

The system is suitable for multiplex panel validation and pathway studies. Focus areas include stem cell pluripotency studies, cancer research using FFPE samples, multiplex microbial detection for respiratory virus identification and food and beverage bacteria and yeast characterisation. The system also supports researchers who have completed their initial discovery work from the literature or large-scale screening technologies. The system is used for multiplexed, quantitative gene expression analysis as well as a multipurpose genetic analysis platform.