Drug target screening panels

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Applied Biosystems has introduced four gene signature panels as part of its TaqMan low density array range for real-time PCR applications.

The arrays include the human G protein-coupled receptors panel, human protein kinase panel, mouse immune panel and human endogenous controls panel.

The human GPCR and human protein kinase panels are important tools for drug target screening and pharmacogenomics research. The mouse immune panel contains genes known for their involvement in inflammation, cancer and cell proliferation making it a tool for disease association studies, while the endogenous control panel allows researchers to select the most appropriate controls for experiments. The low density arrays are 384-well micro-fluidic cards designed for analysing gene expression patterns in many samples across a defined set of gene targets.

They streamline reaction set-up, reduce reagent consumption and require no liquid-handling robotics. Using gold standard chemistry for quantitative gene expression, the array gene signature panels offer researchers the accuracy, sensitivity and high reproducibility of real-time PCR using TaqMan assays with pre-configured panels for target screening and disease association research.