Sigma Life Science and Cofactor Genomics rat genome database

Friday, 15 April, 2011 | Supplied by: Merck


Sigma Life Science’s SAGE Labs initiative has partnered with Cofactor Genomics in an effort to sequence genomes for six of the most widely used strains of rat. As part of the agreement, Cofactor Genomics plans to generate and analyse sequence data using next-generation sequencing systems, while SAGE Labs plans to provide the samples and to host a new, free public database at sageresearchmodels.com in late 2011. The database will include exclusive genomic information and analysis tools.

Currently, the Brown Norway is the only rat strain with a high-quality draft sequence available. It was completed by the Rat Genome Consortium in 2004 with funding from the NIH. The draft sequence showed the rat shares nearly every gene implicated in human disease. However, since then, little work has been done, with the last update occurring in November 2004.

The additional genome sequence provided by SAGE Labs and Cofactor Genomics should enable SAGE Labs to create improved models of human disease for the research community, while helping researchers to better pinpoint the crucial areas of biological difference between rats and humans. The creation of a new, public rat strain database could provide a quantum leap forward for better understanding the genetic basis of disease in humans.

Online: www.sigmaaldrich.com
Phone: 02 9841 0555
Related Products

Bio-Rad Laboratories StarBright Dyes for spectral flow cytometry

The range provides users with more options when designing spectral flow cytometry panels,...

MaxWell Biosystems MaxOne+ HD-MEA Chip

The MaxOne+ HD-MEA Chip provides an upgraded performance and user experience through...

Immundiagnostik ID-Vit MTP assays

Immundiagnostik's ID-Vit MTP assays range enables the quantification of all eight...


  • All content Copyright © 2025 Westwick-Farrow Pty Ltd