Life Scientist > Molecular Biology

CRISPR gene-editing tool targets RNA, tackles dementia

19 March, 2018 by Lauren Davis

Scientists have used CRISPR gene-editing technology to target RNA — as opposed to DNA — and in the process corrected a protein imbalance in cells from a dementia patient.


DNA scissors can cut RNA as well

08 March, 2018

Scientists have discovered that Cas9 'DNA scissors' can also readily target RNA, in a breakthrough that could have far-reaching ramifications.


Scientists identify genes linked to specific diseases

07 March, 2018

UQ researchers are using what is said to be the largest set of multilevel genomic data ever compiled to pinpoint the genes within our DNA that are linked to specific diseases.


Familial breast cancer not only inherited genetically

02 March, 2018

Researchers have identified heritable but non-genetic markers for breast cancer susceptibility, in a breakthrough that will enable doctors to better predict cancer risk.


Genetic variation and harsh habitats help fish resist climate change

02 February, 2018 by Lauren Davis

The DNA of freshwater fish in the Murray–Darling Basin provides clues as to which species have natural resilience against climate change.


RNA mimic blocks pain at a molecular level

18 January, 2018

US researchers are using RNA-based medicine to combat one of the most pervasive of human health conditions — pain.


Atomic structure revealed for blood flow-regulating protein

22 December, 2017

US scientists have revealed for the first time the atomic-level structure of a promising drug target for conditions such as stroke and traumatic brain injury, with the results published in the journal Nature.


Modified gene-editing technique reverses disease without cutting DNA

21 December, 2017

Californian researchers have developed a modified CRISPR-Cas9 technique that alters the activity, rather than the underlying sequence, of disease-associated genes.


Bacteria genomes hold blueprints for anticancer drugs

20 December, 2017

Scientists have 'mined' the information stored in bacteria genomes, which they suggest hold the blueprints for new, effective cancer-targeting compounds.


New protein functions uncovered

19 December, 2017

Scientists have developed a new approach to identify important undiscovered functions of proteins.


Scientists find possible genetic links to male sexual orientation

11 December, 2017 by Lauren Davis

While Australia's LGBTIQ+ community celebrates the legalisation of same-sex marriage, US researchers are continuing the search for the elusive 'gay gene'.


Illumina NovaSeq Xp sequencing workflow

06 December, 2017

The NovaSeq Xp workflow, for use with the NovaSeq 6000 sequencing system, enables sequencing of different library pools in each lane of the flow cell.


Sequencing technology picks up the "spelling mistakes" in DNA

05 December, 2017

Researchers from South Australia are leading what they believe to be a genomic revolution — and they couldn't have done it without the help of nine-year-old Angus Bond.


Protein analysis provides new insights into Down syndrome

01 December, 2017

European researchers have analysed the proteins of individuals with trisomy 21 — more commonly known as Down syndrome — for the first time.


Reversible 'master switch' for developmental genes discovered

22 November, 2017

Researchers have identified a reversible 'master switch' on most developmental genes in the common fruit fly, a powerful model organism for studying how human genes are organised and function.


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