The guardian of the genome
02 March, 2007 by Graeme O'NeillWhile P53 is most familiar as the master regulator of apoptosis, Scott Lowe says it also eliminates pre-cancerous cells by several other mechanisms, including senescence.
Early Europeans unable to stomach milk
01 March, 2007 by Staff WritersThe first direct evidence that early Europeans were unable to digest milk has been found by scientists at University College London (UCL) and Mainz University in Germany.
Recessive form of brittle bone disease discovered
26 February, 2007 by Kate McDonaldScientists have discovered a new form of osteogenesis imperfecta, commonly known as brittle bone disease.
The platypus laid bare
23 February, 2007 by Graeme O'NeillThe Platypus Genome Project is uncovering some interesting information about the chromosomal makeup of marsupials and monotremes.
Danger: new protein super-family discovered
22 February, 2007 by Staff WritersAmerican researchers have discovered a new super-family of developmental proteins that are critical for cell growth and differentiation.
Single chip for SNPs and copy number variations
19 February, 2007 by Staff WritersAffymetrix has developed a single-chip array to measure SNPs and CNVs.
Cell-based imaging for tissue samples
08 February, 2007 by Kate McDonaldWest Australian biotech Molecular Discovery Systems is using a GE Healthcare image analysis system for a whole new purpose.
Rhomboids give biological heresy a cold shower
05 February, 2007 by Graeme O'NeillFour years ago Matthew Freeman discovered the first of a new family of membrane-active protease enzymes, rhomboids. They disturbed the sleep of biophysicists, but are now inspiring drug researchers to dream.
Proteins while you wait
05 February, 2007 by Fiona WylieThe need for high-throughput methods for rapid, larger scale purification and production of recombinant proteins is a major challenge for biomedical research. A team from Monash University is taking that challenge.
The genes that maketh the man
25 January, 2007 by Graeme O'NeillA Melbourne research team has identified a gene which when deleted causes male-to-female sex reversal in XY mice.
Sex and the single toad
22 January, 2007 by Fiona WyliePut away the cricket bats: scientists are using sex as weapon in the fight against the menace that is the cane toad.
When p is greater than n
19 January, 2007 by Kate McDonaldCrunching the numbers from multivariate statistics sounds a rather dry topic to wet lab specialists, but a group of CSIRO researchers has taken a rather philosophical approach to managing the data mountain.
Common parasite genome sequenced
17 January, 2007 by Staff WritersThe genome of the Trichomonas vaginalis parasite, responsible for a common sexually transmitted disease, has been sequenced.
Decoded sea urchin genome shows surprising relationship to humans
17 November, 2006 by External Press Release AuthorThe genome of the sea urchin has been sequenced, with discoveries including a novel immune system, unexpected sensory proteins and a broad similarity to human genes.
RNAi: sense and antisense
15 November, 2006 by Kate McDonaldGene silencing by small interfering RNAs (siRNAs) has emerged as an extremely useful technology for discovery biology, but off-target activity has proved a stumbling block. Detailed mechanistic insights and chemical modification of siRNAs can now improve the robustness of RNAi experiments, as Kate McDonald reports.
