Life Scientist > Molecular Biology

Dicer and double-stranded RNAs

15 November, 2006 by Steve Kulisch

Bio-Rad Laboratories' Steve Kulisch explains how synthetic 27-mer double-stranded RNAs can be designed to be processed by the Dicer endonuclease in a more predictable and efficient way.


How Big Blue created the Blue Gene and is now delving into the Blue Brain

15 November, 2006 by Kate McDonald

How did a chemistry PhD become one of the 50 most powerful women in business by hooking up the world's largest computer company with the life sciences? Kate McDonald spoke to IBM's Carol Kovac, who admits to being rather excited about the world of biology.


Newly discovered proteins associated with cystic fibrosis

07 November, 2006 by ABN Staff

Researchers have found a highly unusual distribution of two proteins in the lungs and airways of people with cystic fibrosis, a discovery that could be a step in determining how the disease progresses.


Genetic riddle solved by kangaroo and platypus

06 November, 2006 by ABN Staff

Australian scientists have unravelled a mystery behind the evolutionary origins of two debilitating human genetic diseases by studying the kangaroo and platypus genome.


100 genomes, 10 days and 10 million dollars

05 October, 2006 by ABN Staff

The US-based X Prize Foundation has launched an audacious competition to find a private company that can successfully map 100 human genomes in just 10 days. The winner will receive US$10 million (AU$13.75m).


US scientists win Nobel Prize for RNA interference discovery

03 October, 2006 by ABN Staff

American geneticists Andrew Fire and Craig Mello have won the 2006 Nobel Prize in Physiology or Medicine for their discovery of RNA interference, a mechanism for controlling the flow of genetic information.


Blackburn wins Lasker award for telomerase research

29 September, 2006 by ABN Staff

Australian-born molecular biologist Professor Elizabeth Blackburn has won the prestigious Lasker Award for the discovery of telomerase, the enzyme that synthesises telomeres, the tiny units of DNA that seal off the ends of chromosomes.


R-nomics and the central dogma of biology

21 September, 2006 by Graeme O'Neill

Professor John Mattick is challenging the orthodoxy that selfish DNA is the cornerstone of the genome. Regulatory RNA is where it's all happening, as Graeme O'Neill reports.


The next generation in sequencing is SOLiD

21 July, 2006 by Kate McDonald

Applied Biosystems hopes to introduce a brand new technology for DNA sequencing to the global market next year.


Flipping over a molecular mousetrap

21 July, 2006 by Kate McDonald

ANU researchers have uncovered a neat little system to stop DNA replication in its tracks.


Chromosome 1: the biography

21 July, 2006 by Graeme O'Neill

An annotated DNA sequence for human chromosome 1 was published in Nature in May. Graeme O'Neill takes a time-travelling tour of the big one.


Protein partners and neural transmission

21 July, 2006 by Kate McDonald

The discovery of an important partnership between two proteins in the neuron holds out great hope for treating epilepsy.


Human Variome project gets underway

21 July, 2006 by Graeme O'Neill

The international Human Variome Project is up and running following a highly successful first meeting in Melbourne in June.


The molecular mechanisms of ageing

21 July, 2006 by Fiona Wylie

How and why do we age, can we do anything about it or is our lifespan programmed from the moment of conception?


Depression vulnerability gene confirmed

01 March, 2006 by Graeme O'Neill

An Australian replication study has strengthened evidence that individuals who inherit a common variant of the serotonin transporter gene 5-HTT are more vulnerable to major depression after adverse events in their lives.


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