Bruker amazon speed and amazon speed ETD ion trap mass spectrometers

Bruker has released its high-performance amazon speed and amazon speed ETD ion trap mass spectrometers (ITMS) to meet the increasing demands of the proteomics, research and applied markets.

Claimed to be the world’s fastest ion trap, the amazon speed offers high ion trap mass accuracy and mass resolution. All amazon speed scan modes offer improved resolution: the fast XtremeScan (52,000 µm/s) now features mass resolution better than 0.5 µm for resolving doubly charged ions. The Maximum Resolution Mode (5200 µm/s) enables mass resolution well below 0.1 µm and can resolve 8+ multiply charged ions in full scans across a wide ITMS mass range (up to m/z 3000). Other major achievements in hardware and software result in an MS/MS duty cycle of 8 Hz.

This high raw ITMS performance enables analytical capabilities for proteomics researchers for both bottom-up and top-down strategies. In combination with SMART precursor ion isolation and fragmentation, routine, unambiguous identification of ~1300 proteins is now possible in single amazon speed LC/MS/MS runs of, for example, 1 μg E. coli lysate.

For both top-down applications and post-translational modifications, the system delivers sensitive, robust and reliable set-up. In combination with Bruker’s GlycoQuest glycan DB search engine, the amazon speed can be used to retrieve structures of released glycans in an easy, automated approach.

The enhanced performance of the amazon speed also delivers greatly improved data quality in a wide range of small molecule applications. Quantification of therapeutic drugs is fully enabled by very sensitive and fast LC-MS/MS methods taking less than 5 minutes.

The amazon speed is a robust system suitable for a multi-user environment.